CTPS2 Antibody - #DF12590
| Product: | CTPS2 Antibody |
| Catalog: | DF12590 |
| Description: | Rabbit polyclonal antibody to CTPS2 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 66 kDa; 66kD(Calculated). |
| Uniprot: | Q9NRF8 |
| RRID: | AB_2845552 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12590, RRID:AB_2845552.
Fold/Unfold
CTP synthase 2; CTP synthase II; CTP synthetase 2; CTPS2; CYTIDINE 5 PRIME TRIPHOSPHATE SYNTHETASE 2; FLJ43358; MGC32997; PYRG2_HUMAN; UTP--ammonia ligase 2;
Immunogens
- Q9NRF8 PYRG2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKYILVTGGVISGIGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQHVINKERRGDYLGKTVQVVPHITDAVQEWVMNQAKVPVDGNKEEPQICVIELGGTIGDIEGMPFVEAFRQFQFKAKRENFCNIHVSLVPQLSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSSTPIEMAVKEKISMFCHVNPEQVICIHDVSSTYRVPVLLEEQSIVKYFKERLHLPIGDSASNLLFKWRNMADRYERLQKICSIALVGKYTKLRDCYASVFKALEHSALAINHKLNLMYIDSIDLEKITETEDPVKFHEAWQKLCKADGILVPGGFGIRGTLGKLQAISWARTKKIPFLGVCLGMQLAVIEFARNCLNLKDADSTEFRPNAPVPLVIDMPEHNPGNLGGTMRLGIRRTVFKTENSILRKLYGDVPFIEERHRHRFEVNPNLIKQFEQNDLSFVGQDVDGDRMEIIELANHPYFVGVQFHPEFSSRPMKPSPPYLGLLLAATGNLNAYLQQGCKLSSSDRYSDASDDSFSEPRIAELEIS
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NRF8 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S12 | Phosphorylation | Uniprot | |
| Y53 | Phosphorylation | Uniprot | |
| K92 | Ubiquitination | Uniprot | |
| K100 | Ubiquitination | Uniprot | |
| K169 | Methylation | Uniprot | |
| T189 | Phosphorylation | Uniprot | |
| K195 | Ubiquitination | Uniprot | |
| R205 | Methylation | Uniprot | |
| S261 | Phosphorylation | Uniprot | |
| K264 | Ubiquitination | Uniprot | |
| S277 | Phosphorylation | Uniprot | |
| Y336 | Phosphorylation | Uniprot | |
| K353 | Ubiquitination | Uniprot | |
| K360 | Ubiquitination | Uniprot | |
| T378 | Phosphorylation | Uniprot | |
| R389 | Methylation | Uniprot | |
| K466 | Ubiquitination | Uniprot | |
| S562 | Phosphorylation | Uniprot | |
| S563 | Phosphorylation | Uniprot | |
| S564 | Phosphorylation | Uniprot | |
| R566 | Methylation | Uniprot | |
| Y567 | Phosphorylation | Uniprot | |
| S568 | Phosphorylation | P48729 (CSNK1A1) | Uniprot |
| S571 | Phosphorylation | Uniprot | |
| S574 | Phosphorylation | Uniprot | |
| S576 | Phosphorylation | Uniprot |
Research Backgrounds
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides.
Belongs to the CTP synthase family.
Research Fields
· Metabolism > Nucleotide metabolism > Pyrimidine metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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