CPOX Antibody - #DF12588
| Product: | CPOX Antibody |
| Catalog: | DF12588 |
| Description: | Rabbit polyclonal antibody to CPOX |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Rabbit |
| Mol.Wt.: | 36 kDa; 50kD(Calculated). |
| Uniprot: | P36551 |
| RRID: | AB_2845550 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12588, RRID:AB_2845550.
Fold/Unfold
Coprogen oxidase; COPROPORPHYRIA; Coproporphyrinogen III oxidase; Coproporphyrinogen Oxidase (CPOX); Coproporphyrinogen-III oxidase; Coproporphyrinogenase; COX; CPO; Cpox; CPX; HEM 6; Hem-6; Hem6; HEM6_HUMAN; mitochondrial;
Immunogens
- P36551 HEM6_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALQLGRLSSGPCWLVARGGCGGPRAWSQCGGGGLRAWSQRSAAGRVCRPPGPAGTEQSRGLGHGSTSRGGPWVGTGLAAALAGLVGLATAAFGHVQRAEMLPKTSGTRATSLGRPEEEEDELAHRCSSFMAPPVTDLGELRRRPGDMKTKMELLILETQAQVCQALAQVDGGANFSVDRWERKEGGGGISCVLQDGCVFEKAGVSISVVHGNLSEEAAKQMRSRGKVLKTKDGKLPFCAMGVSSVIHPKNPHAPTIHFNYRYFEVEEADGNKQWWFGGGCDLTPTYLNQEDAVHFHRTLKEACDQHGPDLYPKFKKWCDDYFFIAHRGERRGIGGIFFDDLDSPSKEEVFRFVQSCARAVVPSYIPLVKKHCDDSFTPQEKLWQQLRRGRYVEFNLLYDRGTKFGLFTPGSRIESILMSLPLTARWEYMHSPSENSKEAEILEVLRHPRDWVR
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P36551 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S112 | Phosphorylation | Uniprot | |
| K184 | Ubiquitination | Uniprot | |
| K220 | Ubiquitination | Uniprot | |
| R298 | Methylation | Uniprot | |
| K301 | Ubiquitination | Uniprot | |
| K314 | Ubiquitination | Uniprot | |
| K347 | Ubiquitination | Uniprot | |
| S356 | Phosphorylation | Uniprot | |
| K370 | Ubiquitination | Uniprot | |
| K404 | Acetylation | Uniprot | |
| K404 | Ubiquitination | Uniprot | |
| T409 | Phosphorylation | Uniprot | |
| S416 | Phosphorylation | Uniprot | |
| S420 | Phosphorylation | Uniprot | |
| T424 | Phosphorylation | Uniprot | |
| K438 | Ubiquitination | Uniprot |
Research Backgrounds
Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
Mitochondrion intermembrane space.
Homodimer.
Belongs to the aerobic coproporphyrinogen-III oxidase family.
Research Fields
· Metabolism > Metabolism of cofactors and vitamins > Porphyrin and chlorophyll metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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