Product: MSI2H Antibody
Catalog: DF12552
Description: Rabbit polyclonal antibody to MSI2H
Application: WB
Reactivity: Human, Mouse, Rat
Prediction: Pig, Rabbit, Chicken, Xenopus
Mol.Wt.: 35 kDa; 35kD(Calculated).
Uniprot: Q96DH6
RRID: AB_2845514

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Rabbit(100%), Chicken(100%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
MSI2H Antibody detects endogenous levels of total MSI2H.
RRID:
AB_2845514
Cite Format: Affinity Biosciences Cat# DF12552, RRID:AB_2845514.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

FLJ36569; MGC3245; Msi2; MSI2/HOXA9 fusion gene, included; MSI2H; MSI2H_HUMAN; Musashi 2; Musashi homolog 2; Musashi RNA binding protein 2; Musashi, Drosophila, homolog of, 2; Musashi-2; RNA binding protein Musashi homolog 2; RNA-binding protein Musashi homolog 2; WD 40 repeat protein MSI2;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q96DH6 MSI2H_HUMAN:

Ubiquitous; detected at low levels.

Sequence:
MEANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYGYQFPGFPAAAYGPVAAAAVAAARGSGSNPARPGGFPGANSPGPVADLYGPASQDSGVGNYISAASPQPGSGFGHGIAGPLIATAFTNGYH

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Xenopus
100
Chicken
100
Rabbit
100
Horse
0
Bovine
0
Sheep
0
Dog
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q96DH6 As Substrate

Site PTM Type Enzyme
M1 Acetylation
S6 Phosphorylation
T9 Phosphorylation
S16 Phosphorylation
T32 Phosphorylation
S33 Phosphorylation
K43 Acetylation
K43 Ubiquitination
K59 Ubiquitination
S74 Phosphorylation
K77 Ubiquitination
K89 Ubiquitination
K94 Ubiquitination
K104 Ubiquitination
Y129 Phosphorylation
K135 Ubiquitination
K145 Ubiquitination
K166 Ubiquitination
K178 Ubiquitination
R197 Methylation
R199 Methylation
R201 Methylation
R228 Methylation
R261 Methylation

Research Backgrounds

Function:

RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).

PTMs:

Phosphorylated.

Subcellular Location:

Cytoplasm.
Note: Associated with polysomes.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitous; detected at low levels.

Family&Domains:

Belongs to the Musashi family.

Research Fields

· Genetic Information Processing > Translation > mRNA surveillance pathway.

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