Product: MTCH1 Antibody
Catalog: DF12524
Description: Rabbit polyclonal antibody to MTCH1
Application: WB
Reactivity: Human
Prediction: Pig, Bovine
Mol.Wt.: 42 kDa; 42kD(Calculated).
Uniprot: Q9NZJ7
RRID: AB_2845486

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Pig(100%), Bovine(100%)
Clonality:
Polyclonal
Specificity:
MTCH1 Antibody detects endogenous levels of total MTCH1.
RRID:
AB_2845486
Cite Format: Affinity Biosciences Cat# DF12524, RRID:AB_2845486.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Cell proliferation inducing protein 60; CGI64; Mitochondrial carrier homolog 1; MTCH 1; Mtch1; MTCH1_HUMAN; Presenilin associated protein; Presenilin-associated protein; PSAP;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9NZJ7 MTCH1_HUMAN:

Widely expressed with a predominant expression in brain.

Sequence:
MGASDPEVAPWARGGAAGMAGAGAGAGARGGAAAGVEARARDPPPAHRAHPRHPRPAAQPSARRMDGGSGGLGSGDNAPTTEALFVALGAGVTALSHPLLYVKLLIQVGHEPMPPTLGTNVLGRKVLYLPSFFTYAKYIVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEIEQVSNKDDMKTSLKKVVKETSYEMMMQCVSRMLAHPLHVISMRCMVQFVGREAKYSGVLSSIGKIFKEEGLLGFFVGLIPHLLGDVVFLWGCNLLAHFINAYLVDDSVSDTPGGLGNDQNPGSQFSQALAIRSYTKFVMGIAVSMLTYPFLLVGDLMAVNNCGLQAGLPPYSPVFKSWIHCWKYLSVQGQLFRGSSLLFRRVSSGSCFALE

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Horse
0
Sheep
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9NZJ7 As Substrate

Site PTM Type Enzyme
S4 Phosphorylation
R29 Methylation
S61 Phosphorylation
S96 Phosphorylation
K125 Ubiquitination
Y128 Phosphorylation
S158 Phosphorylation
K171 Ubiquitination
K184 Ubiquitination
K188 Ubiquitination
S381 Phosphorylation
S382 Phosphorylation
S384 Phosphorylation

Research Backgrounds

Function:

Potential mitochondrial transporter. May play a role in apoptosis.

Subcellular Location:

Mitochondrion inner membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Widely expressed with a predominant expression in brain.

Subunit Structure:

Interacts with PSEN1.

Family&Domains:

Belongs to the mitochondrial carrier (TC 2.A.29) family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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