Peripherin Antibody - #AF0242
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF0242, RRID:AB_2833417.
Fold/Unfold
NEF 4; NEF4; Neurofilament 4 (57kD); Neurofilament 4; Perf; PERI_HUMAN; Peripherin; PRPH 1; prph; PRPH1;
Immunogens
- P41219 PERI_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSHHPSGLRAGFSSTSYRRTFGPPPSLSPGAFSYSSSSRFSSSRLLGSASPSSSVRLGSFRSPRAGAGALLRLPSERLDFSMAEALNQEFLATRSNEKQELQELNDRFANFIEKVRFLEQQNAALRGELSQARGQEPARADQLCQQELRELRRELELLGRERDRVQVERDGLAEDLAALKQRLEEETRKREDAEHNLVLFRKDVDDATLSRLELERKIESLMDEIEFLKKLHEEELRDLQVSVESQQVQQVEVEATVKPELTAALRDIRAQYESIAAKNLQEAEEWYKSKYADLSDAANRNHEALRQAKQEMNESRRQIQSLTCEVDGLRGTNEALLRQLRELEEQFALEAGGYQAGAARLEEELRQLKEEMARHLREYQELLNVKMALDIEIATYRKLLEGEESRISVPVHSFASLNIKTTVPEVEPPQDSHSRKTVLIKTIETRNGEVVTESQKEQRSELDKSSAHSY
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P41219 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S13 | Phosphorylation | Uniprot | |
| Y17 | Phosphorylation | Uniprot | |
| S28 | Phosphorylation | Uniprot | |
| S50 | Phosphorylation | Uniprot | |
| S59 | Phosphorylation | P31749 (AKT1) | Uniprot |
| S62 | Phosphorylation | Uniprot | |
| S75 | Phosphorylation | Uniprot | |
| K98 | Methylation | Uniprot | |
| Y287 | Phosphorylation | Uniprot | |
| K288 | Acetylation | Uniprot | |
| K288 | Ubiquitination | Uniprot | |
| K290 | Ubiquitination | Uniprot | |
| K398 | Acetylation | Uniprot | |
| K398 | Sumoylation | Uniprot | |
| K398 | Ubiquitination | Uniprot | |
| S405 | Phosphorylation | Uniprot | |
| S413 | Phosphorylation | Uniprot | |
| T421 | Phosphorylation | Uniprot | |
| Y470 | Phosphorylation | Uniprot |
Research Backgrounds
Class-III neuronal intermediate filament protein.
Belongs to the intermediate filament family.
Research Fields
· Human Diseases > Neurodegenerative diseases > Amyotrophic lateral sclerosis (ALS).
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