PMM2 Antibody - #DF12455
| Product: | PMM2 Antibody |
| Catalog: | DF12455 |
| Description: | Rabbit polyclonal antibody to PMM2 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 28-30 kDa; 28kD(Calculated). |
| Uniprot: | O15305 |
| RRID: | AB_2845260 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12455, RRID:AB_2845260.
Fold/Unfold
AI585868; BOS_22465; C86848; CDG 1; CDG1; CDG1a; CDGS; MGC127449; Phosphomannomutase 2; PMM 2; Pmm2; PMM2_HUMAN;
Immunogens
- O15305 PMM2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O15305 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| K26 | Ubiquitination | Uniprot | |
| K34 | Ubiquitination | Uniprot | |
| S47 | Phosphorylation | Uniprot | |
| K51 | Ubiquitination | Uniprot | |
| K63 | Ubiquitination | Uniprot | |
| Y76 | Phosphorylation | Uniprot | |
| K77 | Ubiquitination | Uniprot | |
| S130 | Phosphorylation | Uniprot | |
| S137 | Phosphorylation | Uniprot | |
| Y145 | Phosphorylation | Uniprot | |
| K149 | Acetylation | Uniprot | |
| K156 | Ubiquitination | Uniprot | |
| K202 | Ubiquitination | Uniprot |
Research Backgrounds
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
Cytoplasm.
Homodimer.
Belongs to the eukaryotic PMM family.
Research Fields
· Metabolism > Carbohydrate metabolism > Fructose and mannose metabolism.
· Metabolism > Carbohydrate metabolism > Amino sugar and nucleotide sugar metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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