OXA1L Antibody | Affinity Biosciences

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Western blot analysis of extracts from various samples, using OXA1L Antibody.

Product:	OXA1L Antibody
Catalog:	DF12437
Description:	Rabbit polyclonal antibody to OXA1L
Application:	WB IHC
Reactivity:	Human, Mouse, Rat
Prediction:	Pig, Bovine, Horse, Sheep, Rabbit, Dog
Mol.Wt.:	42 kDa; 49kD(Calculated).
Uniprot:	Q15070
RRID:	AB_2845242

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

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Related Downloads

MS Report

HPLC Report

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human,Mouse,Rat

Prediction:

Pig(92%), Bovine(92%), Horse(92%), Sheep(92%), Rabbit(92%), Dog(100%)

Clonality:

Polyclonal

Specificity:

OXA1L Antibody detects endogenous levels of total OXA1L.

RRID:

AB_2845242
Cite Format: Affinity Biosciences Cat# DF12437, RRID:AB_2845242.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

HSA; Mitochondrial inner membrane protein OXA1L; OXA1; OXA1 like protein; OXA1-like protein; OXA1Hs; Oxa1l; OXA1L_HUMAN; Oxidase (cytochrome c) assembly 1 like; Oxidase assembly 1 like protein; Oxidase assembly 1-like protein;

Immunogens

Immunogen:

Uniprot:

Q15070(OXA1L_HUMAN) >>Visit HPA database.

Gene(ID):

OXA1L(5018)

Sequence:

Q15070 OXA1L_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MAMGLMCGRRELLRLLQSGRRVHSVAGPSQWLGKPLTTRLLFPVAPCCCRPHYLFLAASGPRSLSTSAISFAEVQVQAPPVVAATPSPTAVPEVASGETADVVQTAAEQSFAELGLGSYTPVGLIQNLLEFMHVDLGLPWWGAIAACTVFARCLIFPLIVTGQREAARIHNHLPEIQKFSSRIREAKLAGDHIEYYKASSEMALYQKKHGIKLYKPLILPVTQAPIFISFFIALREMANLPVPSLQTGGLWWFQDLTVSDPIYILPLAVTATMWAVLELGAETGVQSSDLQWMRNVIRMMPLITLPITMHFPTAVFMYWLSSNLFSLVQVSCLRIPAVRTVLKIPQRVVHDLDKLPPREGFLESFKKGWKNAEMTRQLREREQRMRNQLELAARGPLRQTFTHNPLLQPGKDNPPNIPSSSSKPKSKYPWHDTLG

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species

Results

Score

Dog

100

Pig

Horse

Bovine

Sheep

Rabbit

Xenopus

Zebrafish

Chicken

Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q15070 As Substrate

Q15070

Site	PTM Type	Source
K178	Ubiquitination	Uniprot
K187	Ubiquitination	Uniprot
K197	Ubiquitination	Uniprot
T340	Phosphorylation	Uniprot
K343	Ubiquitination	Uniprot
K354	Ubiquitination	Uniprot
S364	Phosphorylation	Uniprot
K366	Ubiquitination	Uniprot
K370	Ubiquitination	Uniprot
R394	Methylation	Uniprot
T400	Phosphorylation	Uniprot
T402	Phosphorylation	Uniprot
K411	Ubiquitination	Uniprot

Research Backgrounds

Q15070_OXA1L_HUMAN

Function:

Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome oxidase. Required for the correct biogenesis of ATP synthase and complex I in mitochondria.

Subcellular Location:

Mitochondrion inner membrane>Multi-pass membrane protein.

Subunit Structure:

Monomer; predominantly monomeric at low salt concentrations. Homooligomer; predominantly homooligomeric at high salt concentrations. Homodimer. Homotetramer. Interacts with MRPL13, MRPL20, MRPL28, MRPL48, MRPL49 and MRPL51. Associates preferentially as a dimer with the large ribosomal subunit 39S of the mitochondrial ribosome.

Family&Domains:

Belongs to the OXA1/ALB3/YidC family.

Research Fields

· Genetic Information Processing > Folding, sorting and degradation > Protein export.

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OXA1L Antibody - #DF12437