Product: HBS1L Antibody
Catalog: DF12410
Description: Rabbit polyclonal antibody to HBS1L
Application: WB IHC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Zebrafish, Bovine, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 75 kDa; 75kD(Calculated).
Uniprot: Q9Y450
RRID: AB_2845215

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Zebrafish(89%), Bovine(100%), Rabbit(100%), Dog(100%), Chicken(90%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
HBS1L Antibody detects endogenous levels of total HBS1L.
RRID:
AB_2845215
Cite Format: Affinity Biosciences Cat# DF12410, RRID:AB_2845215.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

EF 1a; ERF3 similar protein; ERFS; HBS1; HBS1 like; HBS1 like protein; HBS1, S. cerevisiae, homolog of; HBS1-like (S. cerevisiae); HBS1-like protein; Hbs1l; HBS1L_HUMAN; Hsp70 subfamily B suppressor 1 like protein; HSPC276; KIAA1038;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9Y450 HBS1L_HUMAN:

Detected in heart, brain, placenta, liver, muscle, kidney and pancreas.

Sequence:
MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTAAQFIYSRRDKPSVEPVEEYDYEDLKESSNSVSNHQLSGFDQARLYSCLDHMREVLGDAVPDEILIEAVLKNKFDVQKALSGVLEQDRVQSLKDKNEATVSTGKIAKGKPVDSQTSRSESEIVPKVAKMTVSGKKQTMGFEVPGVSSEENGHSFHTPQKGPPIEDAIASSDVLETASKSANPPHTIQASEEQSSTPAPVKKSGKLRQQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVGFIPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMPPNETCTVKGITLHDEPVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFRARILIFNIEIPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQTQRPIALELYKDFKELGRFMLRYGGSTIAAGVVTEIKE

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Dog
100
Xenopus
100
Rabbit
100
Chicken
90
Zebrafish
89
Sheep
50
Horse
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9Y450 As Substrate

Site PTM Type Enzyme
Y10 Phosphorylation
Y12 Phosphorylation
Y22 Phosphorylation
Y30 Phosphorylation
S33 Phosphorylation
T36 Phosphorylation
Y42 Phosphorylation
K47 Ubiquitination
S49 Phosphorylation
Y56 Phosphorylation
Y58 Phosphorylation
K62 Ubiquitination
S64 Phosphorylation
S65 Phosphorylation
S67 Phosphorylation
S69 Phosphorylation
Y82 Phosphorylation
K107 Ubiquitination
K109 Ubiquitination
K114 Ubiquitination
S117 Phosphorylation
R124 Methylation
S127 Phosphorylation
K140 Ubiquitination
K143 Ubiquitination
S149 Phosphorylation
S152 Phosphorylation
S154 Phosphorylation
S182 Phosphorylation
S189 Phosphorylation
T192 Phosphorylation
T211 Phosphorylation
S215 Phosphorylation
S229 Phosphorylation
S230 Phosphorylation
T231 Phosphorylation
K248 Ubiquitination
K294 Acetylation
Y309 Phosphorylation
T325 Phosphorylation
K332 Ubiquitination
K424 Ubiquitination
K430 Ubiquitination
K435 Ubiquitination
S456 Phosphorylation
K463 Ubiquitination
Y465 Phosphorylation
K466 Ubiquitination
K478 Ubiquitination
K486 Ubiquitination
K497 Ubiquitination
Y513 Phosphorylation
T516 Phosphorylation
T528 Phosphorylation
T530 Phosphorylation
K572 Ubiquitination
K622 Ubiquitination
K657 Ubiquitination

Research Backgrounds

Tissue Specificity:

Detected in heart, brain, placenta, liver, muscle, kidney and pancreas.

Family&Domains:

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family.

Research Fields

· Genetic Information Processing > Translation > mRNA surveillance pathway.

· Human Diseases > Infectious diseases: Bacterial > Legionellosis.

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