EGFL7 Antibody - #DF12391
Product: | EGFL7 Antibody |
Catalog: | DF12391 |
Description: | Rabbit polyclonal antibody to EGFL7 |
Application: | WB IHC |
Reactivity: | Human, Mouse, Rat |
Prediction: | Pig, Horse, Dog, Chicken |
Mol.Wt.: | 41-45 kDa; 30kD(Calculated). |
Uniprot: | Q9UHF1 |
RRID: | AB_2845196 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12391, RRID:AB_2845196.
Fold/Unfold
EGF like domain 7; EGF like domain containing protein 7; EGF like domain multiple 7; EGF-like protein 7; EGFL 7; EGFL7; EGFL7_HUMAN; Epidermal growth factor like domain protein 7; Epidermal growth factor-like protein 7; MEGF 7; MEGF7; MGC111117; Multiple EGF like domain protein 7; Multiple EGF-like domains protein 7; Multiple epidermal growth factor like domain protein 7; Multiple epidermal growth factor-like domains protein 7; NEU1; NEU1 protein; NOTCH4 like protein; NOTCH4-like protein; RP11 251M1.2; UNQ187/PRO1449; Vascular endothelial statin; VE statin; VE-statin; ZNEU 1; ZNEU1;
Immunogens
- Q9UHF1 EGFL7_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRGSQEVLLMWLLVLAVGGTEHAYRPGRRVCAVRAHGDPVSESFVQRVYQPFLTTCDGHRACSTYRTIYRTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKGGPPRVAPNPTGVDSAMKEEVQRLQSRVDLLEEKLQLVLAPLHSLASQALEHGLPDPGSLLVHSFQQLGRIDSLSEQISFLEEQLGSCSCKKDS
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UHF1 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
Y49 | Phosphorylation | Uniprot | |
T54 | O-Glycosylation | Uniprot | |
T54 | Phosphorylation | Uniprot | |
T55 | O-Glycosylation | Uniprot | |
Y65 | Phosphorylation | Uniprot | |
K93 | Ubiquitination | Uniprot | |
T190 | O-Glycosylation | Uniprot | |
K197 | Ubiquitination | Uniprot |
Research Backgrounds
Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cell adhesion to the extracellular matrix and angiogenesis.
Secreted>Extracellular space.
Interacts with ITGAV/ITGB3 in an RGD-dependent manner, increasing endothelial cell's motility.
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