CRLS1 Antibody - #DF12373
| Product: | CRLS1 Antibody |
| Catalog: | DF12373 |
| Description: | Rabbit polyclonal antibody to CRLS1 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 50 kDa; 33kD(Calculated). |
| Uniprot: | Q9UJA2 |
| RRID: | AB_2845178 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12373, RRID:AB_2845178.
Fold/Unfold
0610009I22Rik; 4930557M15Rik; 5730490M08; C20orf155; Cardiolipin synthase 1; Cardiolipin synthase; CLS; CLS1; CRLS1; CRLS1_HUMAN; dJ967N21.6; GCD10; OTTMUSP00000016677; Protein GCD10 homolog; RGD1311037; RP23-77H16.4;
Immunogens
- Q9UJA2 CRLS1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLALRVARGSWGALRGAAWAPGTRPSKRRACWALLPPVPCCLGCLAERWRLRPAALGLRLPGIGQRNHCSGAGKAAPRPAAGAGAAAEAPGGQWGPASTPSLYENPWTIPNMLSMTRIGLAPVLGYLIIEEDFNIALGVFALAGLTDLLDGFIARNWANQRSALGSALDPLADKILISILYVSLTYADLIPVPLTYMIISRDVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTFISKVNTAVQLILVAASLAAPVFNYADSIYLQILWCFTAFTTAASAYSYYHYGRKTVQVIKD
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UJA2 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K225 | Ubiquitination | Uniprot | |
| K294 | Ubiquitination | Uniprot |
Research Backgrounds
Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.
Mitochondrion inner membrane>Multi-pass membrane protein.
Highly expressed in tissues such as heart, skeletal muscle and liver.
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
Research Fields
· Metabolism > Lipid metabolism > Glycerophospholipid metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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