FECH Antibody - #DF12273
| Product: | FECH Antibody |
| Catalog: | DF12273 |
| Description: | Rabbit polyclonal antibody to FECH |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 46 kDa; 48kD(Calculated). |
| Uniprot: | P22830 |
| RRID: | AB_2845078 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12273, RRID:AB_2845078.
Fold/Unfold
EPP; FCE; Fch; Fcl; fech; Ferrochelatase (protoporphyria); Ferrochelatase; Ferrochelatase mitochondrial; Heme synthase; Heme synthetase; HEMH_HUMAN; mitochondrial; Protoheme ferro lyase; Protoheme ferro-lyase; Protoporphyria;
Immunogens
- P22830 HEMH_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQVQPQKRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P22830 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K37 | Acetylation | Uniprot | |
| T49 | Phosphorylation | Uniprot | |
| K57 | Ubiquitination | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| S130 | Phosphorylation | Uniprot | |
| S151 | Phosphorylation | Uniprot | |
| Y210 | Phosphorylation | Uniprot | |
| S303 | Phosphorylation | Uniprot | |
| K304 | Ubiquitination | Uniprot | |
| T315 | Phosphorylation | Uniprot | |
| S318 | Phosphorylation | Uniprot | |
| K320 | Ubiquitination | Uniprot | |
| K415 | Acetylation | Uniprot | |
| S420 | Phosphorylation | Uniprot |
Research Backgrounds
Catalyzes the ferrous insertion into protoporphyrin IX.
Mitochondrion inner membrane>Peripheral membrane protein>Matrix side.
Homodimer.
Belongs to the ferrochelatase family.
Research Fields
· Metabolism > Metabolism of cofactors and vitamins > Porphyrin and chlorophyll metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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