PRPH2 Antibody - #DF12223
| Product: | PRPH2 Antibody |
| Catalog: | DF12223 |
| Description: | Rabbit polyclonal antibody to PRPH2 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 39 kDa; 39kD(Calculated). |
| Uniprot: | P23942 |
| RRID: | AB_2845028 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12223, RRID:AB_2845028.
Fold/Unfold
AOFMD; AVMD; CACD2; DS; Peripherin 2 (retinal degeneration, slow); Peripherin 2, homolog of mouse; Peripherin, photoreceptor type; Peripherin-2; PRPH; PRPH2; PRPH2_HUMAN; Rd2; RDS; Retinal degeneration slow protein; Retinal peripherin; RP7; Tetraspanin-22; Tspan-22; TSPAN22;
Immunogens
- P23942 PRPH2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALLKVKFDQKKRVKLAQGLWLMNWFSVLAGIIIFSLGLFLKIELRKRSDVMNNSESHFVPNSLIGMGVLSCVFNSLAGKICYDALDPAKYARWKPWLKPYLAICVLFNIILFLVALCCFLLRGSLENTLGQGLKNGMKYYRDTDTPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEIQWISNRYLDFSSKEVKDRIKSNVDGRYLVDGVPFSCCNPSSPRPCIQYQITNNSAHYSYDHQTEELNLWVRGCRAALLSYYSSLMNSMGVVTLLIWLFEVTITIGLRYLQTSLDGVSNPEESESESEGWLLEKSVPETWKAFLESVKKLGKGNQVEAEGAGAGQAPEAG
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P23942 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y184 | Phosphorylation | Uniprot | |
| S189 | Phosphorylation | Uniprot |
Research Backgrounds
Essential for retina photoreceptor outer segment disk morphogenesis, may also play a role with ROM1 in the maintenance of outer segment disk structure (By similarity). Required for the maintenance of retinal outer nuclear layer thickness (By similarity). Required for the correct development and organization of the photoreceptor inner segment (By similarity).
Membrane>Multi-pass membrane protein. Cell projection>Cilium>Photoreceptor outer segment. Photoreceptor inner segment.
Retina (photoreceptor). In rim region of ROS (rod outer segment) disks.
Homodimer; disulfide-linked (By similarity). Forms a homotetramer (By similarity). Forms a heterotetramer with ROM1 (By similarity). Homotetramer and heterotetramer core complexes go on to form higher order complexes by formation of intermolecular disulfide bonds (By similarity). Interacts with MREG (By similarity). Interacts with STX3 (By similarity). Interacts with SNAP25 (By similarity).
Belongs to the PRPH2/ROM1 family.
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