ELAC2 Antibody - #DF12153
| Product: | ELAC2 Antibody |
| Catalog: | DF12153 |
| Description: | Rabbit polyclonal antibody to ELAC2 |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 92 kDa; 92kD(Calculated). |
| Uniprot: | Q9BQ52 |
| RRID: | AB_2844958 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12153, RRID:AB_2844958.
Fold/Unfold
COXPD17; elaC homolog 2 (E. coli); ElaC homolog protein 2; elaC ribonuclease Z 2; elaC, E. coli, homolog of, 2; ELAC2; ELC2; FLJ10530; FLJ36693; FLJ42848; Heredity prostate cancer protein 2; HPC2; putative prostate cancer susceptibility protein HPC2/ELAC2; Ribonuclease Z 2; Ribonuclease Z, long form; Ribonuclease Z2; RNase Z 2; RNase Z2; RNase ZL; RNZ2_HUMAN; tRNA 3 endonuclease 2; tRNase Z (long form); tRNase Z 2; tRNase Z2; Zinc phosphodiesterase ELAC protein 2;
Immunogens
Widely expressed. Highly expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, testis and ovary. Weakly expressed in brain, lung, spleen, thymus, prostate, small intestine, colon and leukocytes.
- Q9BQ52 RNZ2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFNCGEGVQRLMQEHKLKVARLDNIFLTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLEKYLEAIKIFSGPLKGIELAVRPHSAPEYEDETMTVYQIPIHSEQRRGKHQPWQSPERPLSRLSPERSSDSESNENEPHLPHGVSQRRGVRDSSLVVAFICKLHLKRGNFLVLKAKEMGLPVGTAAIAPIIAAVKDGKSITHEGREILAEELCTPPDPGAAFVVVECPDESFIQPICENATFQRYQGKADAPVALVVHMAPASVLVDSRYQQWMERFGPDTQHLVLNENCASVHNLRSHKIQTQLNLIHPDIFPLLTSFRCKKEGPTLSVPMVQGECLLKYQLRPRREWQRDAIITCNPEEFIVEALQLPNFQQSVQEYRRSAQDGPAPAEKRSQYPEIIFLGTGSAIPMKIRNVSATLVNISPDTSLLLDCGEGTFGQLCRHYGDQVDRVLGTLAAVFVSHLHADHHTGLPSILLQRERALASLGKPLHPLLVVAPNQLKAWLQQYHNQCQEVLHHISMIPAKCLQEGAEISSPAVERLISSLLRTCDLEEFQTCLVRHCKHAFGCALVHTSGWKVVYSGDTMPCEALVRMGKDATLLIHEATLEDGLEEEAVEKTHSTTSQAISVGMRMNAEFIMLNHFSQRYAKVPLFSPNFSEKVGVAFDHMKVCFGDFPTMPKLIPPLKALFAGDIEEMEERREKRELRQVRAALLSRELAGGLEDGEPQQKRAHTEEPQAKKVRAQ
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9BQ52 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R28 | Methylation | Uniprot | |
| K99 | Methylation | Uniprot | |
| K101 | Methylation | Uniprot | |
| K135 | Ubiquitination | Uniprot | |
| K146 | Ubiquitination | Uniprot | |
| K152 | Acetylation | Uniprot | |
| K152 | Ubiquitination | Uniprot | |
| Y181 | Phosphorylation | Uniprot | |
| K193 | Ubiquitination | Uniprot | |
| S199 | Phosphorylation | Uniprot | |
| S205 | Phosphorylation | Uniprot | |
| S208 | Phosphorylation | Uniprot | |
| S212 | Phosphorylation | Uniprot | |
| S213 | Phosphorylation | Uniprot | |
| S215 | Phosphorylation | Uniprot | |
| S217 | Phosphorylation | Uniprot | |
| S229 | Phosphorylation | Uniprot | |
| S238 | Phosphorylation | Uniprot | |
| K260 | Ubiquitination | Uniprot | |
| K279 | Acetylation | Uniprot | |
| K279 | Ubiquitination | Uniprot | |
| K282 | Ubiquitination | Uniprot | |
| K332 | Ubiquitination | Uniprot | |
| K384 | Ubiquitination | Uniprot | |
| K407 | Ubiquitination | Uniprot | |
| K424 | Ubiquitination | Uniprot | |
| K476 | Ubiquitination | Uniprot | |
| K495 | Ubiquitination | Uniprot | |
| Y528 | Phosphorylation | Uniprot | |
| K571 | Ubiquitination | Uniprot | |
| K608 | Ubiquitination | Uniprot | |
| S618 | Phosphorylation | Uniprot | |
| K678 | Ubiquitination | Uniprot | |
| T688 | Phosphorylation | Uniprot | |
| T701 | Phosphorylation | Uniprot | |
| K731 | Ubiquitination | Uniprot | |
| S736 | Phosphorylation | Uniprot | |
| S740 | Phosphorylation | Uniprot | |
| K742 | Ubiquitination | Uniprot | |
| K751 | Ubiquitination | Uniprot | |
| K762 | Ubiquitination | Uniprot | |
| K768 | Ubiquitination | Uniprot | |
| K811 | Ubiquitination | Uniprot |
Research Backgrounds
Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
Mitochondrion. Nucleus.
Note: Mainly mitochondrial.
Widely expressed. Highly expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, testis and ovary. Weakly expressed in brain, lung, spleen, thymus, prostate, small intestine, colon and leukocytes.
Homodimer (By similarity). Interacts with PTCD1.
Belongs to the RNase Z family.
Research Fields
· Genetic Information Processing > Translation > RNA transport.
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