MTA3 Antibody - #DF12121
| Product: | MTA3 Antibody |
| Catalog: | DF12121 |
| Description: | Rabbit polyclonal antibody to MTA3 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 62 kDa,68 kDa; 68kD(Calculated). |
| Uniprot: | Q9BTC8 |
| RRID: | AB_2844926 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12121, RRID:AB_2844926.
Fold/Unfold
1110002J22Rik; fj99h01; KIAA1266; Metastasis associated 1 family, member 3; Metastasis associated 3; Metastasis associated family, member 3; Metastasis associated gene 3; Metastasis associated gene family, member 3; Metastasis associated protein MTA3; Metastasis-associated protein MTA3; MGC56396; MGC77410; mKIAA1266; mta1; Mta3; MTA3 metastasis associated 1 family, member 3; Mta3 metastasis associated 3; MTA3_HUMAN; wu:fj99h01; zgc:56396;
Immunogens
Expressed in germinal centers of lymphoid tissues. No expression in nonepithelial cells.
- Q9BTC8 MTA3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLADKHAKEIEEESETTVEADLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDTFFYSLVYDPSLKTLLADKGEIRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYSKPNPNQISTSNGKPGAVNGAVGTTFQPQNPLLGRACESCYATQSHQWYSWGPPNMQCRLCAICWLYWKKYGGLKMPTQSEEEKLSPSPTTEDPRVRSHVSRQAMQGMPVRNTGSPKSAVKTRQAFFLHTTYFTKFARQVCKNTLRLRQAARRPFVAINYAAIRAEYADRHAELSGSPLKSKSTRKPLACIIGYLEIHPAKKPNVIRSTPSLQTPTTKRMLTTPNHTSLSILGKRNYSHHNGLDELTCCVSD
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9BTC8 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y11 | Phosphorylation | Uniprot | |
| K32 | Ubiquitination | Uniprot | |
| T33 | Phosphorylation | Uniprot | |
| Y46 | Phosphorylation | Uniprot | |
| K61 | Ubiquitination | Uniprot | |
| T72 | Phosphorylation | Uniprot | |
| T73 | Phosphorylation | Uniprot | |
| K147 | Ubiquitination | Uniprot | |
| S186 | Phosphorylation | Uniprot | |
| S213 | Phosphorylation | Uniprot | |
| S214 | Phosphorylation | Uniprot | |
| S215 | Phosphorylation | Uniprot | |
| R217 | Methylation | Uniprot | |
| S224 | Phosphorylation | Uniprot | |
| K288 | Ubiquitination | Uniprot | |
| K323 | Ubiquitination | Uniprot | |
| S422 | Phosphorylation | Uniprot | |
| K426 | Ubiquitination | Uniprot | |
| S428 | Phosphorylation | Uniprot | |
| S430 | Phosphorylation | Uniprot | |
| T432 | Phosphorylation | Uniprot | |
| T455 | Phosphorylation | Uniprot | |
| S457 | Phosphorylation | Uniprot | |
| S517 | Phosphorylation | Uniprot | |
| S519 | Phosphorylation | Uniprot | |
| S553 | Phosphorylation | Uniprot | |
| T565 | Phosphorylation | Uniprot | |
| S593 | Phosphorylation | Uniprot |
Research Backgrounds
Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6.
Nucleus.
Expressed in germinal centers of lymphoid tissues. No expression in nonepithelial cells.
Component of the nucleosome-remodeling and histone-deacetylase multiprotein complex (NuRD). Interacts with BCL6. Interacts with NACC2.
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