GNMT Antibody - #DF12117
| Product: | GNMT Antibody |
| Catalog: | DF12117 |
| Description: | Rabbit polyclonal antibody to GNMT |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 33 kDa; 33kD(Calculated). |
| Uniprot: | Q14749 |
| RRID: | AB_2844922 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12117, RRID:AB_2844922.
Fold/Unfold
EC 2.1.1.20; Glycine N methyltransferase; Glycine N-methyltransferase; Gnmt; GNMT_HUMAN; OTTHUMP00000016412;
Immunogens
- Q14749 GNMT_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYDHILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSKFRLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQTYIPCYFIHVLKRTD
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q14749 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S10 | Phosphorylation | P17612 (PRKACA) | Uniprot |
| Y22 | Phosphorylation | Uniprot | |
| Y34 | Phosphorylation | Uniprot | |
| S81 | Phosphorylation | Uniprot | |
| K97 | Acetylation | Uniprot | |
| Y196 | Phosphorylation | Uniprot | |
| Y197 | Phosphorylation | Uniprot | |
| S199 | Phosphorylation | Uniprot | |
| T220 | Phosphorylation | Uniprot | |
| T224 | Phosphorylation | Uniprot | |
| S235 | Phosphorylation | Uniprot | |
| S252 | Phosphorylation | Uniprot |
Research Backgrounds
Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine.
Cytoplasm.
Abundant in liver.
Homotetramer.
Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.
Research Fields
· Metabolism > Amino acid metabolism > Glycine, serine and threonine metabolism.
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