TMPRSS4 Antibody - #DF12037
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Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12037, RRID:AB_2844842.
Fold/Unfold
UNQ776/PRO1570; CAPH2; Channel-activating protease 2; Membrane type serine protease 2; Membrane-type serine protease 2; MT SP2; MT-SP2; TMPRSS 4; TMPRSS3; TMPRSS4; TMPS4_HUMAN; Transmembrane protease serine 4; Transmembrane protease, serine 4; Transmembrane serine protease 3;
Immunogens
High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract.
- Q9NRS4 TMPS4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLQDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKYYFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSATGNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSSGPCLSGSLVSLHCLACGKSLKTPRVVGVEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWIYNVWKAEL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NRS4 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T28 | Phosphorylation | Uniprot |
Research Backgrounds
Probable protease. Seems to be capable of activating ENaC (By similarity).
Membrane>Single-pass type II membrane protein.
High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract.
Belongs to the peptidase S1 family.
Research Fields
· Human Diseases > Infectious diseases: Viral > Influenza A.
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