SAR1A Antibody - #AF4630
| Product: | SAR1A Antibody |
| Catalog: | AF4630 |
| Description: | Rabbit polyclonal antibody to SAR1A |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Chicken, Xenopus |
| Mol.Wt.: | 22kDa; 22kD(Calculated). |
| Uniprot: | Q9NR31 |
| RRID: | AB_2844577 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF4630, RRID:AB_2844577.
Fold/Unfold
COPII associated small GTPase; COPII-associated small GTPase; GTP binding protein SAR1a; GTP-binding protein SAR1a; Masra 2; Masra2; SAR 1; SAR1 gene homolog A; SAR1 homolog A (S. cerevisiae); SAR1A; SAR1a gene homolog (S cerevisiae) 1; SAR1a gene homolog 1 (S cerevisiae); SAR1a gene homolog 1; SAR1A_HUMAN; SARA 1; Sara; SARA1;
Immunogens
- Q9NR31 SAR1A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLVESKVELNALMTDETISNVPILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFMCSVLKRQGYGEGFRWLSQYID
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NR31 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K27 | Ubiquitination | Uniprot | |
| T39 | Phosphorylation | Uniprot | |
| T40 | Phosphorylation | Uniprot | |
| K46 | Ubiquitination | Uniprot | |
| T60 | Phosphorylation | Uniprot | |
| Y89 | Phosphorylation | Uniprot | |
| T120 | Phosphorylation | Uniprot | |
| T123 | Phosphorylation | Uniprot | |
| S125 | Phosphorylation | Uniprot | |
| T139 | Phosphorylation | Uniprot | |
| S143 | Phosphorylation | Uniprot | |
| K146 | Acetylation | Uniprot | |
| K146 | Ubiquitination | Uniprot | |
| Y154 | Phosphorylation | Uniprot | |
| T164 | Phosphorylation | Uniprot | |
| K166 | Ubiquitination | Uniprot | |
| K182 | Ubiquitination | Uniprot |
Research Backgrounds
Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).
Endoplasmic reticulum. Golgi apparatus.
Interacts with B3GAT1.
Belongs to the small GTPase superfamily. SAR1 family.
Research Fields
· Genetic Information Processing > Folding, sorting and degradation > Protein processing in endoplasmic reticulum. (View pathway)
· Human Diseases > Infectious diseases: Bacterial > Legionellosis.
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