PDE6G Antibody - #DF10358

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Product: PDE6G Antibody
Catalog: DF10358
Description: Rabbit polyclonal antibody to PDE6G
Application: WB
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Dog, Chicken, Xenopus
Mol.Wt.: 9KD; 10kD(Calculated).
Uniprot: P18545
RRID: AB_2844365

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Dog(100%), Chicken(100%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
PDE6G Antibody detects endogenous levels of total PDE6G.
RRID:
AB_2844365
Cite Format: Affinity Biosciences Cat# DF10358, RRID:AB_2844365.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

5''-cyclic phosphodiesterase subunit gamma; CNRG_HUMAN; GMP-PDE gamma; MGC125749; PDE 6; PDE6G; PDEG; Phosphodiesterase 6G cGMP Specific; Phosphodiesterase 6G cGMP specific rog gamma; Retinal Rod Photoreceptor cGMP Phosphodiesterase gamma; Retinal rod rhodopsin sensitive cGMP 3' 5'vcyclic phosphodiesterase subunit gamma; Retinal rod rhodopsin-sensitive cGMP 3''; Rod cG PDE G; RP57;

Immunogens

Immunogen:
Uniprot:

P18545(CNRG_HUMAN) >>Visit HPA database.

Gene(ID):
PDE6G(5148)
Sequence:
MNLEPPKAEFRSATRVAGGPVTPRKGPPKFKQRQTRQFKSKPPKKGVQGFGDDIPGMEGLGTDITVICPWEAFNHLELHELAQYGII

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Chicken
100
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P18545 As Substrate

Site PTM Type Enzyme
T22 Phosphorylation P27361 (MAPK3)
K25 Ubiquitination
R36 Methylation
T62 Phosphorylation A0A0S2Z3I6 (ADRBK1) , P25098 (GRK2)

Research Backgrounds

Function:

Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

Subunit Structure:

Oligomer composed of two catalytic chains (alpha and beta), an inhibitory chain (gamma) and the delta chain.

Family&Domains:

Belongs to the rod/cone cGMP-PDE gamma subunit family.

Research Fields

· Metabolism > Nucleotide metabolism > Purine metabolism.

· Organismal Systems > Sensory system > Phototransduction.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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