USP22 Antibody - #AF7576
| Product: | USP22 Antibody |
| Catalog: | AF7576 |
| Description: | Rabbit polyclonal antibody to USP22 |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 66kDa; 60kD(Calculated). |
| Uniprot: | Q9UPT9 |
| RRID: | AB_2843940 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF7576, RRID:AB_2843940.
Fold/Unfold
Deubiquitinating enzyme 22; KIAA1063; Ubiquitin carboxyl terminal hydrolase 22; Ubiquitin carboxyl-terminal hydrolase 22; Ubiquitin specific peptidase 22; Ubiquitin specific peptidase 3 like; Ubiquitin specific processing protease 22; Ubiquitin specific protease 22; Ubiquitin thioesterase 22; Ubiquitin thiolesterase 22; Ubiquitin-specific-processing protease 22; UBP22_HUMAN; USP 22; Usp22; USP3L;
Immunogens
A synthesized peptide derived from human USP22, corresponding to a region within the internal amino acids.
Moderately expressed in various tissues including heart and skeletal muscle, and weakly expressed in lung and liver.
- Q9UPT9 UBP22_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVSRPEPEGEAMDAELAVAPPGCSHLGSFKVDNWKQNLRAIYQCFVWSGTAEARKRKAKSCICHVCGVHLNRLHSCLYCVFFGCFTKKHIHEHAKAKRHNLAIDLMYGGIYCFLCQDYIYDKDMEIIAKEEQRKAWKMQGVGEKFSTWEPTKRELELLKHNPKRRKITSNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHRCEMQSPSSCLVCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDNGKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSEGNVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPTDSLNNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLDSEGYLLFYHKQFLEYE
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
Research Backgrounds
Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
Nucleus.
Moderately expressed in various tissues including heart and skeletal muscle, and weakly expressed in lung and liver.
Belongs to the peptidase C19 family. UBP8 subfamily.
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