CTGF Antibody - #AF7537
| Product: | CTGF Antibody |
| Catalog: | AF7537 |
| Description: | Rabbit polyclonal antibody to CTGF |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Sheep, Rabbit, Chicken |
| Mol.Wt.: | 38kDa; 38kD(Calculated). |
| Uniprot: | P29279 |
| RRID: | AB_2843901 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF7537, RRID:AB_2843901.
Fold/Unfold
CCN 2; CCN family member 2; CCN2; Connective tissue growth factor; Ctgf; CTGF_HUMAN; Hcs 24; Hcs24; Hypertrophic chondrocyte specific protein 24; Hypertrophic chondrocyte-specific gene product 24; Hypertrophic chondrocyte-specific protein 24; IBP-8; IGF-binding protein 8; IGFBP-8; IGFBP8; Insulin like Growth Factor Binding Protein 8; Insulin-like growth factor-binding protein 8; MGC102839; NOV 2; NOV2;
Immunogens
Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested.
- P29279 CCN2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKGLFCHFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDMA
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P29279 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K91 | Ubiquitination | Uniprot | |
| S118 | Phosphorylation | Uniprot | |
| Y122 | Phosphorylation | Uniprot | |
| S145 | Phosphorylation | Uniprot | |
| T193 | O-Glycosylation | Uniprot | |
| T219 | Phosphorylation | Uniprot | |
| T222 | Phosphorylation | Uniprot | |
| S234 | Phosphorylation | Uniprot | |
| T322 | Phosphorylation | Uniprot | |
| Y340 | Phosphorylation | Uniprot |
Research Backgrounds
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
Secreted>Extracellular space>Extracellular matrix. Secreted.
Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested.
Monomer.
Belongs to the CCN family.
Research Fields
· Environmental Information Processing > Signal transduction > Apelin signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > Hippo signaling pathway. (View pathway)
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