Product: FABP7 Antibody
Catalog: AF7534
Description: Rabbit polyclonal antibody to FABP7
Application: WB
Reactivity: Human, Mouse
Prediction: Pig, Bovine, Horse, Sheep, Dog, Chicken, Xenopus
Mol.Wt.: 15kDa; 15kD(Calculated).
Uniprot: O15540
RRID: AB_2843898

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Bovine(88%), Horse(88%), Sheep(100%), Dog(100%), Chicken(100%), Xenopus(88%)
Clonality:
Polyclonal
Specificity:
FABP7 Antibody detects endogenous levels of total FABP7.
RRID:
AB_2843898
Cite Format: Affinity Biosciences Cat# AF7534, RRID:AB_2843898.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

B FABP; B-FABP; BFABP; BLBP; Brain lipid binding protein; Brain lipid-binding protein; Brain-type fatty acid-binding protein; DKFZp547J2313; FABP 7; FABP7; FABP7_HUMAN; FABPB; Fatty Acid Binding Protein 7; Fatty acid binding protein 7 brain; Fatty acid binding protein brain; Fatty acid-binding protein 7; Fatty acid-binding protein, brain; Mammary derived growth inhibitor related; Mammary-derived growth inhibitor related; MRG; OTTHUMP00000017119;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
O15540 FABP7_HUMAN:

Expressed in brain and other neural tissues.

Sequence:
MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTFKNTEISFQLGEEFDETTADDRNCKSVVSLDGDKLVHIQKWDGKETNFVREIKDGKMVMTLTFGDVVAVRHYEKA

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Sheep
100
Dog
100
Chicken
100
Horse
88
Bovine
88
Xenopus
88
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O15540 As Substrate

Site PTM Type Enzyme
T54 Phosphorylation
T57 Phosphorylation
T61 Phosphorylation
T117 Phosphorylation
T119 Phosphorylation
Y129 Phosphorylation

Research Backgrounds

Function:

B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers (By similarity).

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in brain and other neural tissues.

Family&Domains:

Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.

Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Research Fields

· Organismal Systems > Endocrine system > PPAR signaling pathway.

Restrictive clause

 

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For Research Use Only.
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