Gz alpha Antibody - #AF0091
| Product: | Gz alpha Antibody |
| Catalog: | AF0091 |
| Description: | Rabbit polyclonal antibody to Gz alpha |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat, Monkey |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 41kDa; 41kD(Calculated). |
| Uniprot: | P19086 |
| RRID: | AB_2833274 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF0091, RRID:AB_2833274.
Fold/Unfold
G(x) alpha chain; GNAZ; GNAZ_HUMAN; Guanine nucleotide binding protein (G protein) alpha z polypeptide; Guanine nucleotide binding protein G(z) alpha subunit G(x) alpha chain; Guanine nucleotide binding protein G(z) subunit alpha; Guanine nucleotide-binding protein G(z) subunit alpha; Gz alpha; Gz-alpha; Human Gx alpha gene; Transducin alpha;
Immunogens
- P19086 GNAZ_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALRIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLTICFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P19086 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S16 | Phosphorylation | Q05655 (PRKCD) , Q13153 (PAK1) , P17252 (PRKCA) | Uniprot |
| S27 | Phosphorylation | P17252 (PRKCA) , Q05655 (PRKCD) | Uniprot |
| T41 | Phosphorylation | Uniprot | |
| K51 | Ubiquitination | Uniprot | |
| S142 | Phosphorylation | Uniprot | |
| K189 | Ubiquitination | Uniprot | |
| S229 | Phosphorylation | Uniprot | |
| Y231 | Phosphorylation | Uniprot | |
| T263 | Phosphorylation | Uniprot | |
| S264 | Phosphorylation | Uniprot | |
| T341 | Phosphorylation | Uniprot |
Research Backgrounds
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Membrane>Lipid-anchor.
G-proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with ADGRB2.
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
Research Fields
· Organismal Systems > Nervous system > Long-term depression.
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