Phospho-GATA2 (Ser401) Antibody - #AF7270
| Product: | Phospho-GATA2 (Ser401) Antibody |
| Catalog: | AF7270 |
| Description: | Rabbit polyclonal antibody to Phospho-GATA2 (Ser401) |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat, Monkey |
| Prediction: | Bovine, Horse, Rabbit, Chicken, Xenopus |
| Mol.Wt.: | 49kDa; 51kD(Calculated). |
| Uniprot: | P23769 |
| RRID: | AB_2843710 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF7270, RRID:AB_2843710.
Fold/Unfold
DCML; Endothelial transcription factor GATA 2; Endothelial transcription factor GATA-2; Endothelial transcription factor GATA2; FLJ45948; GATA 2; GATA binding protein 2; GATA-binding protein 2; Gata2; GATA2_HUMAN; IMD21; MGC2306; MONOMAC; NFE 1B; NFE1B; OTTHUMP00000216240;
Immunogens
- P23769 GATA2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGNPYYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHNPWTVSPFSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQPATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKCMQEKSSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMG
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P23769 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S71 | Phosphorylation | Uniprot | |
| S73 | Phosphorylation | Uniprot | |
| R86 | Methylation | Uniprot | |
| S119 | Phosphorylation | Uniprot | |
| T176 | Phosphorylation | P06493 (CDK1) | Uniprot |
| S182 | Phosphorylation | Uniprot | |
| S186 | Phosphorylation | Uniprot | |
| S192 | Phosphorylation | Uniprot | |
| Y213 | Phosphorylation | Uniprot | |
| S216 | Phosphorylation | Uniprot | |
| S220 | Phosphorylation | Uniprot | |
| S276 | Phosphorylation | Uniprot | |
| S290 | Phosphorylation | Uniprot | |
| Y314 | Phosphorylation | Uniprot | |
| Y322 | Phosphorylation | Uniprot | |
| Y376 | Phosphorylation | Uniprot | |
| K389 | Sumoylation | Uniprot | |
| S401 | Phosphorylation | P31749 (AKT1) | Uniprot |
| K409 | Ubiquitination | Uniprot |
Research Backgrounds
Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'.
Nucleus.
Endothelial cells.
Interacts with BRD3 (By similarity). Interacts with AR and CCAR1.
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For Research Use Only.
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