ketohexokinase Antibody - #AF7029
| Product: | ketohexokinase Antibody |
| Catalog: | AF7029 |
| Description: | Rabbit polyclonal antibody to ketohexokinase |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Prediction: | Bovine, Horse, Sheep |
| Mol.Wt.: | 33 KD; 33kD(Calculated). |
| Uniprot: | P50053 |
| RRID: | AB_2843469 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF7029, RRID:AB_2843469.
Fold/Unfold
EC 2.7.1.3; Fructokinase; Hepatic fructokinase; Ketohexokinase; Ketohexokinase isoform a; KHK; KHK_HUMAN;
Immunogens
A synthesized peptide derived from human ketohexokinase, corresponding to a region within N-terminal amino acids.
Most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye.
- P50053 KHK_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P50053 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S90 | Phosphorylation | Uniprot | |
| S116 | Phosphorylation | Uniprot | |
| K134 | Ubiquitination | Uniprot | |
| K148 | Ubiquitination | Uniprot | |
| K197 | Ubiquitination | Uniprot |
Research Backgrounds
Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate.
Most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye.
Homodimer.
Belongs to the carbohydrate kinase PfkB family.
Research Fields
· Metabolism > Carbohydrate metabolism > Fructose and mannose metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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