ZIP2 Antibody - #AF9234

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Product: ZIP2 Antibody
Catalog: AF9234
Description: Rabbit polyclonal antibody to ZIP2
Application: WB IHC IF/ICC
Reactivity: Human
Mol.Wt.: 36kDa; 33kD(Calculated).
Uniprot: Q9NP94
RRID: AB_2843424

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
ZIP2 Antibody detects endogenous levels of total ZIP2.
RRID:
AB_2843424
Cite Format: Affinity Biosciences Cat# AF9234, RRID:AB_2843424.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

hZIP2; 6A1; Eti-1; Eti1; hZIP2; MGC119190; OTTHUMP00000164402; S39A2_HUMAN; SLC39A2; Solute carrier family 39 (zinc transporter) member 2; Solute carrier family 39 member 2; Zinc transporter ZIP2; ZIP 2; ZIP-2; ZIP2; Zrt and Irt like protein 2; Zrt- and Irt-like protein 2;

Immunogens

Immunogen:
Uniprot:

Q9NP94(S39A2_HUMAN) >>Visit HPA database.

Gene(ID):
SLC39A2(29986)
Expression:
Q9NP94 S39A2_HUMAN:

Expressed only in prostate and uterine epithelial cells.

Sequence:
MEQLLGIKLGCLFALLALTLGCGLTPICFKWFQIDAARGHHRLVLRLLGCISAGVFLGAGFMHMTAEALEEIESQIQKFMVQNRSASERNSSGDADSAHMEYPYGELIISLGFFFVFFLESLALQCCPGAAGGSTVQDEEWGGAHIFELHSHGHLPSPSKGPLRALVLLLSLSFHSVFEGLAVGLQPTVAATVQLCLAVLAHKGLVVFGVGMRLVHLGTSSRWAVFSILLLALMSPLGLAVGLAVTGGDSEGGRGLAQAVLEGVAAGTFLYVTFLEILPRELASPEAPLAKWSCVAAGFAFMAFIALWA

Research Backgrounds

Function:

Mediates zinc uptake. Zinc uptake may be mediated by a Zn(2+)-HCO(3)(-) symport mechanism and can function in the presence of albumin. May also transport other divalent cations. May be important in contact inhibition of normal epithelial cells and loss of its expression may play a role in tumorigenesis.

Subcellular Location:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed only in prostate and uterine epithelial cells.

Family&Domains:

Belongs to the ZIP transporter (TC 2.A.5) family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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