Histamine H4 Receptor Antibody - #AF9086
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| Product: | Histamine H4 Receptor Antibody |
| Catalog: | AF9086 |
| Description: | Rabbit polyclonal antibody to Histamine H4 Receptor |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human |
| Mol.Wt.: | 45kDa; 44kD(Calculated). |
| Uniprot: | Q9H3N8 |
| RRID: | AB_2843277 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF9086, RRID:AB_2843277.
Fold/Unfold
AXOR35; BG26; G protein coupled receptor 105; G-protein coupled receptor 105; GPCR105; GPRv53; H4; H4R; HH4R; Histamine H4 receptor; Histamine receptor H4; Hrh4; HRH4_HUMAN; Pfi-013; SP9144;
Immunogens
Expressed primarily in the bone marrow and eosinophils. Shows preferential distribution in cells of immunological relevance such as T-cells, dendritic cells, monocytes, mast cells, neutrophils. Also expressed in a wide variety of peripheral tissues, including the heart, kidney, liver, lung, pancreas, skeletal muscle, prostate, small intestine, spleen, testis, colon, fetal liver and lymph node.
- Q9H3N8 HRH4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDFFVGVISIPLYIPHTLFEWDFGKEICVFWLTTDYLLCTASVYNIVLISYDRYLSVSNAVSYRTQHTGVLKIVTLMVAVWVLAFLVNGPMILVSESWKDEGSECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLTAVSSNICGHSFRGRLSSRRSLSASTEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIKKQPLPSQHSRSVSS
PTMs - Q9H3N8 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S208 | Phosphorylation | Uniprot | |
| S258 | Phosphorylation | Uniprot |
Research Backgrounds
The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist).
Cell membrane>Multi-pass membrane protein.
Expressed primarily in the bone marrow and eosinophils. Shows preferential distribution in cells of immunological relevance such as T-cells, dendritic cells, monocytes, mast cells, neutrophils. Also expressed in a wide variety of peripheral tissues, including the heart, kidney, liver, lung, pancreas, skeletal muscle, prostate, small intestine, spleen, testis, colon, fetal liver and lymph node.
Belongs to the G-protein coupled receptor 1 family.
Research Fields
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
References
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