GBP4 Antibody | Affinity Biosciences

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Western blot analysis of extracts from various samples, using GBP4 Antibody.

Product:	GBP4 Antibody
Catalog:	AF9071
Description:	Rabbit polyclonal antibody to GBP4
Application:	WB
Reactivity:	Human, Mouse, Rat
Mol.Wt.:	73kDa; 73kD(Calculated).
Uniprot:	Q96PP9
RRID:	AB_2843262

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

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Related Downloads

MS Report

HPLC Report

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

WB 1:1000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human,Mouse,Rat

Clonality:

Polyclonal

Specificity:

GBP4 Antibody detects endogenous levels of total GBP4.

RRID:

AB_2843262
Cite Format: Affinity Biosciences Cat# AF9071, RRID:AB_2843262.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

GBP 4; GBP-4; GBP4; GBP4_HUMAN; GTP binding protein 4; GTP-binding protein 4; Guanine nucleotide binding protein 4; Guanine nucleotide-binding protein 4; Guanylate binding protein 4; Guanylate-binding protein 4; Mpa2;

Immunogens

Immunogen:

Uniprot:

Q96PP9(GBP4_HUMAN) >>Visit HPA database.

Gene(ID):

GBP4(115361)

Sequence:

Q96PP9 GBP4_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MGERTLHAAVPTPGYPESESIMMAPICLVENQEEQLTVNSKALEILDKISQPVVVVAIVGLYRTGKSYLMNRLAGKRNGFPLGSTVQSETKGIWMWCVPHLSKPNHTLVLLDTEGLGDVEKSNPKNDSWIFALAVLLSSSFVYNSVSTINHQALEQLHYVTELAELIRAKSCPRPDEAEDSSEFASFFPDFIWTVRDFTLELKLDGNPITEDEYLENALKLIPGKNPKIQNSNMPRECIRHFFRKRKCFVFDRPTNDKQYLNHMDEVPEENLERHFLMQSDNFCSYIFTHAKTKTLREGIIVTGKRLGTLVVTYVDAINSGAVPCLENAVTALAQLENPAAVQRAADHYSQQMAQQLRLPTDTLQELLDVHAACEREAIAVFMEHSFKDENHEFQKKLVDTIEKKKGDFVLQNEEASAKYCQAELKRLSEHLTESILRGIFSVPGGHNLYLEEKKQVEWDYKLVPRKGVKANEVLQNFLQSQVVVEESILQSDKALTAGEKAIAAERAMKEAAEKEQELLREKQKEQQQMMEAQERSFQEYMAQMEKKLEEERENLLREHERLLKHKLKVQEEMLKEEFQKKSEQLNKEINQLKEKIESTKNEQLRLLKILDMASNIMIVTLPGASKLLGVGTKYLGSRI

PTMs - Q96PP9 As Substrate

Q96PP9

Site	PTM Type	Source
T303	Phosphorylation	Uniprot
T401	Phosphorylation	Uniprot
K404	Acetylation	Uniprot
S429	Phosphorylation	Uniprot
T433	Phosphorylation	Uniprot
S435	Phosphorylation	Uniprot
S537	Phosphorylation	Uniprot
K567	Acetylation	Uniprot
S615	Phosphorylation	Uniprot
K634	Ubiquitination	Uniprot

Research Backgrounds

Q96PP9_GBP4_HUMAN

Function:

Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. Plays a role in erythroid differentiation (By similarity).

Subcellular Location:

Cytoplasm. Nucleus. Cytoplasm>Perinuclear region. Golgi apparatus membrane.
Note: Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus.

Subunit Structure:

Heterodimer with other family members, including GBP1, GBP2 and GBP5. Dimerization regulates subcellular location.

Family&Domains:

Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily.

Research Fields

· Organismal Systems > Immune system > NOD-like receptor signaling pathway. (View pathway)

Restrictive clause

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For Research Use Only.
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GBP4 Antibody - #AF9071