Cables2 Antibody | Affinity Biosciences

WB
IF/ICC

1/2

Western blot analysis of Cables2 using Jurkat whole cell lysates.

Product:	Cables2 Antibody
Catalog:	AF9029
Description:	Rabbit polyclonal antibody to Cables2
Application:	WB IF/ICC
Reactivity:	Human, Mouse, Rat
Prediction:	Pig, Dog, Xenopus
Mol.Wt.:	60kDa; 52kD(Calculated).
Uniprot:	Q9BTV7
RRID:	AB_2843220

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

Lead Time: Same day delivery

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Related Downloads

MS Report

HPLC Report

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

WB 1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human,Mouse,Rat

Prediction:

Pig(80%), Dog(82%), Xenopus(83%)

Clonality:

Polyclonal

Specificity:

Cables2 Antibody detects endogenous levels of total Cables2.

RRID:

AB_2843220
Cite Format: Affinity Biosciences Cat# AF9029, RRID:AB_2843220.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

C20orf150; CABLES 2; Cdk5 and Abl enzyme substrate 2; CDK5 and ABL1 enzyme substrate 2; dJ908M14.2; Ik3 2; Interactor with CDK3 2;

Immunogens

Immunogen:

Uniprot:

Q9BTV7(CABL2_HUMAN) >>Visit HPA database.

Gene(ID):

CABLES2(81928)

Sequence:

Q9BTV7 CABL2_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MAAAAAGGAPGPAPGPAGPPPPAAPTSAARAPPQALRRRGDSRRRQAALFFLNNISLDGRPPSLGPGGEKPPPPPAEAREPPAPPPPEPPTGLPARTPAPQGLLSPTQVPTGLGLDGQRQRKRVTSQRCSLEFLEDAVGCAPAQRTKHTSGSPRHKGLKKTHFIKNMRQYDTRNSRIVLICAKRSLCAAFSVLPYGEGLRISDLRVDSQKQRHPSGGVSVSSEMVFELEGVELGADGKVVSYAKFLYPTNALVTHKSDSHGLLPTPRPSVPRTLPGSRHKPAPTKSAPASTELGSDVGDTLEYNPNLLDDPQWPCGKHKRVLIFASYMTTVIEYVKPSDLKKDMNETFREKFPHVKLTLSKIRSLKREMRSLSEECSLEPVTVAMAYVYFEKLVLQGKLSKQNRKLCAGACVLLAAKISSDLRKSGVTQLIDKLEERFRFNRRDLIGFEFTVLVALELALYLPENQVLPHYRRLTQQF

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species

Results

Score

Xenopus

Dog

Pig

Bovine

Sheep

Chicken

Horse

Zebrafish

Rabbit

Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9BTV7 As Substrate

Q9BTV7

Site	PTM Type	Source
T97	Phosphorylation	Uniprot
S105	Phosphorylation	Uniprot
T107	Phosphorylation	Uniprot
S126	Phosphorylation	Uniprot
S130	Phosphorylation	Uniprot
S150	Phosphorylation	Uniprot
S208	Phosphorylation	Uniprot
S259	Phosphorylation	Uniprot
T265	Phosphorylation	Uniprot
S269	Phosphorylation	Uniprot
Y327	Phosphorylation	Uniprot
Y334	Phosphorylation	Uniprot
K361	Ubiquitination	Uniprot

Research Backgrounds

Q9BTV7_CABL2_HUMAN

Function:

Unknown. Probably involved in G1-S cell cycle transition.

Subunit Structure:

Binds to CDK3, CDK5 and ABL1. The C-terminal cyclin-box-like region binds to CDK5 (By similarity).

Family&Domains:

Belongs to the cyclin family.

Restrictive clause

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.

Cables2 Antibody - #AF9029