Product: AIFL Antibody
Catalog: AF9005
Description: Rabbit polyclonal antibody to AIFL
Application: WB
Reactivity: Human, Mouse
Prediction: Pig, Bovine, Rabbit, Dog
Mol.Wt.: 67kDa; 67kD(Calculated).
Uniprot: Q96NN9
RRID: AB_2843196

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:1000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Bovine(100%), Rabbit(88%), Dog(100%)
Clonality:
Polyclonal
Specificity:
AIFL Antibody detects endogenous levels of total AIFL.
RRID:
AB_2843196
Cite Format: Affinity Biosciences Cat# AF9005, RRID:AB_2843196.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

AIFL; Aifm3; AIFM3_HUMAN; Apoptosis inducing factor 3; Apoptosis inducing factor like; Apoptosis inducing factor like protein; Apoptosis inducing factor, mitochondrion associated; Apoptosis-inducing factor 3; Apoptosis-inducing factor-like protein; FLJ30473; FLJ45137;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q96NN9 AIFM3_HUMAN:

Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).

Sequence:
MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRAYQGNGTARHFHTEERLSTPHPYPSPQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQLQRRTKVMAKCISPSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSLDTQPEQLALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGSSPKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNVVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFVLHSKTGDMSWLTGKGS

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Dog
100
Rabbit
88
Horse
0
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q96NN9 As Substrate

Site PTM Type Enzyme
S36 Phosphorylation
T45 Phosphorylation
S415 Phosphorylation
T433 Phosphorylation
S439 Phosphorylation
S445 Phosphorylation
T470 Phosphorylation
S605 Phosphorylation

Research Backgrounds

Function:

Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.

Subcellular Location:

Mitochondrion.
Note: Does not translocate to the nucleus upon induction of apoptosis.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).

Family&Domains:

The Rieske domain induces apoptosis.

Belongs to the FAD-dependent oxidoreductase family.

Restrictive clause

 

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For Research Use Only.
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