Product: SCNM1 Antibody
Catalog: DF9928
Description: Rabbit polyclonal antibody to SCNM1
Application: WB IHC
Reactivity: Human, Rat, Monkey
Prediction: Bovine, Horse, Sheep
Mol.Wt.: 26 kDa; 26kD(Calculated).
Uniprot: Q9BWG6
RRID: AB_2843122

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Rat,Monkey
Prediction:
Bovine(100%), Horse(100%), Sheep(100%)
Clonality:
Polyclonal
Specificity:
SCNM1 Antibody detects endogenous levels of total SCNM1.
RRID:
AB_2843122
Cite Format: Affinity Biosciences Cat# DF9928, RRID:AB_2843122.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

SCNM 1; Sodium channel modifier 1;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MSFKREGDDWSQLNVLKKRRVGDLLASYIPEDEALMLRDGRFACAICPHRPVLDTLAMLTAHRAGKKHLSSLQLFYGKKQPGKERKQNPKHQNELRREETKAEAPLLTQTRLITQSALHRAPHYNSCCRRKYRPEAPGPSVSLSPMPPSEVKLQSGKISREPEPAAGPQAEESATVSAPAPMSPTRRRALDHYLTLRSSGWIPDGRGRWVKDENVEFDSDEEEPPDLPLD

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Bovine
100
Sheep
100
Dog
75
Pig
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9BWG6 As Substrate

Site PTM Type Enzyme
S2 Phosphorylation
K17 Ubiquitination
Y76 Phosphorylation
K101 Ubiquitination
S126 Phosphorylation
S144 Phosphorylation
S159 Phosphorylation
S183 Phosphorylation
Y193 Phosphorylation
T195 Phosphorylation
S219 Phosphorylation

Research Backgrounds

Function:

Plays a role in alternative splicing of pre-mRNAs, possibly by contributing to the selection of non-consensus donor sites.

Subcellular Location:

Nucleus>Nucleoplasm. Nucleus speckle.
Note: Colocalizes with LUC7L2 and SNRNP70 in nuclear speckles.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Interacts with spliceosomal Sm proteins. Interacts with LUC7L2 and SNRNP70, which suggests a role as a spliceosome component (By similarity).

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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