RAB33B Antibody - #DF9826
Product: | RAB33B Antibody |
Catalog: | DF9826 |
Description: | Rabbit polyclonal antibody to RAB33B |
Application: | WB IHC |
Reactivity: | Human, Mouse, Rat |
Prediction: | Pig, Bovine, Horse, Sheep, Dog, Chicken |
Mol.Wt.: | 26 kDa; 26kD(Calculated). |
Uniprot: | Q9H082 |
RRID: | AB_2843020 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9826, RRID:AB_2843020.
Fold/Unfold
DKFZP434G099; MGC138182; RAB 33B; RAB33B; RAB33B member RAS oncogene family; Ras related protein Rab 33B; Ras related protein Rab33B; Ras-associated protein RAB33B; Ras-related protein Rab-33B; RB33B_HUMAN; SMC2;
Immunogens
- Q9H082 RB33B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAEEMESSLEASFSSSGAVSGASGFLPPARSRIFKIIVIGDSNVGKTCLTYRFCAGRFPDRTEATIGVDFRERAVEIDGERIKIQLWDTAGQERFRKSMVQHYYRNVHAVVFVYDMTNMASFHSLPSWIEECKQHLLANDIPRILVGNKCDLRSAIQVPTDLAQKFADTHSMPLFETSAKNPNDNDHVEAIFMTLAHKLKSHKPLMLSQPPDNGIILKPEPKPAMTCWC
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9H082 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
T89 | Phosphorylation | Uniprot | |
S98 | Phosphorylation | Uniprot | |
K149 | Ubiquitination | Uniprot | |
K165 | Ubiquitination | Uniprot |
Research Backgrounds
Protein transport. Acts, in coordination with RAB6A, to regulate intra-Golgi retrograde trafficking. It is involved in autophagy, acting as a modulator of autophagosome formation.
Golgi apparatus membrane>Lipid-anchor. Golgi apparatus>cis-Golgi network.
Note: Under starvation conditions punctate RAB33B-positive structures are often observed in the cytoplasm.
Interacts with ATG16L. Interaction with ATG16L is important for autophagosome formation (By similarity). Interacts with RIC1 (via C-terminus domain); the interaction is direct with a preference for RAB33B-GTP. Interacts with RGP1.
Belongs to the small GTPase superfamily. Rab family.
Research Fields
· Cellular Processes > Transport and catabolism > Autophagy - animal. (View pathway)
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