PEX12 Antibody - #DF9739
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9739, RRID:AB_2842934.
Fold/Unfold
CG3; PAF 3; Peroxin 12; Peroxin12; Peroxisomal biogenesis factor 12; Peroxisome assembly factor 3; Peroxisome assembly protein 12; Peroxisome biogenesis disorder, complementation group 3, included; PEX 12;
Immunogens
- O00623 PEX12_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAEHGAHFTAASVADDQPSIFEVVAQDSLMTAVRPALQHVVKVLAESNPTHYGFLWRWFDEIFTLLDLLLQQHYLSRTSASFSENFYGLKRIVMGDTHKSQRLASAGLPKQQLWKSIMFLVLLPYLKVKLEKLVSSLREEDEYSIHPPSSRWKRFYRAFLAAYPFVNMAWEGWFLVQQLRYILGKAQHHSPLLRLAGVQLGRLTVQDIQALEHKPAKASMMQQPARSVSEKINSALKKAVGGVALSLSTGLSVGVFFLQFLDWWYSSENQETIKSLTALPTPPPPVHLDYNSDSPLLPKMKTVCPLCRKTRVNDTVLATSGYVFCYRCVFHYVRSHQACPITGYPTEVQHLIKLYSPEN
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O00623 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K132 | Acetylation | Uniprot | |
| S219 | Phosphorylation | Uniprot | |
| K231 | Acetylation | Uniprot | |
| K237 | Acetylation | Uniprot | |
| S275 | Phosphorylation | Uniprot | |
| T277 | Phosphorylation | Uniprot | |
| T281 | Phosphorylation | Uniprot |
Research Backgrounds
Required for protein import into peroxisomes.
Peroxisome membrane>Multi-pass membrane protein.
Interacts with PEX5 and PEX10. Interacts with PEX19 via its cytoplasmic domain.
Belongs to the pex2/pex10/pex12 family.
Research Fields
· Cellular Processes > Transport and catabolism > Peroxisome. (View pathway)
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