PAOX Antibody - #DF9736
| Product: | PAOX Antibody |
| Catalog: | DF9736 |
| Description: | Rabbit polyclonal antibody to PAOX |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Bovine, Horse, Sheep, Rabbit |
| Mol.Wt.: | 70 kDa; 56kD(Calculated). |
| Uniprot: | Q6QHF9 |
| RRID: | AB_2842931 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9736, RRID:AB_2842931.
Fold/Unfold
DKFZp434J245; MGC45464; PAO; Peroxisomal N(1) acetyl spermine/spermidine oxidase; Peroxisomal N1 acetyl spermine/spermidine oxidase; Polyamine oxidase (exo N4 amino); Polyamine oxidase; RP11 122K13.11;
Immunogens
Widely expressed. Not detected in spleen. Expressed at lower level in neoplastic tissues.
- Q6QHF9 PAOX_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGASVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLKLAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDTVVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFFDPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQLVWEDTSPLEDAAPELQDAWFRKLIGFVVLPAFASVHVLCGFIAGLESEFMETLSDEEVLLCLTQVLRRVTGNPRLPAPKSVLRSRWHSAPYTRGSYSYVAVGSTGGDLDLLAQPLPADGAGAQLQILFAGEATHRTFYSTTHGALLSGWREADRLLSLWAPQVQQPRPRL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6QHF9 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot |
Research Backgrounds
Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.
Peroxisome. Cytoplasm.
Widely expressed. Not detected in spleen. Expressed at lower level in neoplastic tissues.
Monomer.
Belongs to the flavin monoamine oxidase family.
Research Fields
· Cellular Processes > Transport and catabolism > Peroxisome. (View pathway)
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