Product: PEX11A Antibody
Catalog: DF9734
Description: Rabbit polyclonal antibody to PEX11A
Application: WB
Reactivity: Human, Mouse, Rat
Prediction: Bovine, Sheep, Dog
Mol.Wt.: 28 kDa; 28kD(Calculated).
Uniprot: O75192
RRID: AB_2842929

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Bovine(80%), Sheep(90%), Dog(80%)
Clonality:
Polyclonal
Specificity:
PEX11A Antibody detects endogenous levels of total PEX11A.
RRID:
AB_2842929
Cite Format: Affinity Biosciences Cat# DF9734, RRID:AB_2842929.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

28 kDa peroxisomal integral membrane protein; HsPEX11p; MGC119947; MGC138534; Peroxin-11A; Peroxisomal biogenesis factor 11 alpha; Peroxisomal biogenesis factor 11A; Peroxisomal membrane protein 11A; PEX11-alpha; PEX11A; PMP28; Protein PEX11 homolog alpha; PX11A_HUMAN;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MDAFTRFTNQTQGRDRLFRATQYTCMLLRYLLEPKAGKEKVVMKLKKLESSVSTGRKWFRLGNVVHAIQATEQSIHATDLVPRLCLTLANLNRVIYFICDTILWVRSVGLTSGINKEKWRTRAAHHYYYSLLLSLVRDLYEISLQMKRVTCDRAKKEKSASQDPLWFSVAEEETEWLQSFLLLLFRSLKQHPPLLLDTVKNLCDILNPLDQLGIYKSNPGIIGLGGLVSSIAGMITVAYPQMKLKTR

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Sheep
90
Bovine
80
Dog
80
Pig
70
Horse
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O75192 As Substrate

Site PTM Type Enzyme
Y23 Phosphorylation
K47 Ubiquitination
K118 Acetylation
Y127 Phosphorylation
Y128 Phosphorylation
Y129 Phosphorylation

Research Backgrounds

Function:

May be involved in peroxisomal proliferation and may regulate peroxisomes division. May mediate binding of coatomer proteins to the peroxisomal membrane (By similarity). Promotes membrane protrusion and elongation on the peroxisomal surface.

PTMs:

Seems not to be N-glycosylated.

Subcellular Location:

Peroxisome membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Homodimer. Heterodimer with PEX11G. Probably interacts with COPB2 and COPA (By similarity). Interacts with PEX19. Interacts with FIS1.

Family&Domains:

Belongs to the peroxin-11 family.

Research Fields

· Cellular Processes > Transport and catabolism > Peroxisome.   (View pathway)

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