NCR2 Antibody - #DF9677

(3)  
Product: NCR2 Antibody
Catalog: DF9677
Description: Rabbit polyclonal antibody to NCR2
Application: WB IHC
Reactivity: Human
Mol.Wt.: 31 kDa; 31kD(Calculated).
Uniprot: O95944
RRID: AB_2842873

View similar products>>

   Size Price Inventory
 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

For pricing and ordering contact:
Local distributors
Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
NCR2 Antibody detects endogenous levels of total NCR2.
RRID:
AB_2842873
Cite Format: Affinity Biosciences Cat# DF9677, RRID:AB_2842873.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Activating NK receptor NKp44; CD336; CD336 antigen; dJ149M18.1; LY95; Lymphocyte antigen 95 (activating NK receptor; NK p44); Lymphocyte antigen 95 homolog (activating NK receptor; NK p44); Lymphocyte antigen 95 homolog; Lymphocyte antigen 95, mouse, homolog of; Natural cytotoxicity triggering receptor 2; Natural killer cell p44 related protein; Natural killer cell p44-related protein; NCR2; NCTR2_HUMAN; NK cell activating receptor (NKp44); NK cell activating receptor; NK cell-activating receptor; NK p44; NK-p44; NKp44;

Immunogens

Immunogen:
Uniprot:

O95944(NCTR2_HUMAN) >>Visit HPA database.

Gene(ID):
NCR2(9436)
Expression:
O95944 NCTR2_HUMAN:

Selectively expressed by activated NK cells and by in vitro cultured (i.e. activated) TCRg/d lymphoid cells.

Sequence:
MAWRALHPLLLLLLLFPGSQAQSKAQVLQSVAGQTLTVRCQYPPTGSLYEKKGWCKEASALVCIRLVTSSKPRTMAWTSRFTIWDDPDAGFFTVTMTDLREEDSGHYWCRIYRPSDNSVSKSVRFYLVVSPASASTQTSWTPRDLVSSQTQTQSCVPPTAGARQAPESPSTIPVPSQPQNSTLRPGPAAPIALVPVFCGLLVAKSLVLSALLVWWGDIWWKTMMELRSLDTQKATCHLQQVTDLPWTSVSSPVEREILYHTVARTKISDDDDEHTL

PTMs - O95944 As Substrate

Site PTM Type Enzyme
S228 Phosphorylation

Research Backgrounds

Function:

Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

Subcellular Location:

Cell membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Selectively expressed by activated NK cells and by in vitro cultured (i.e. activated) TCRg/d lymphoid cells.

Subunit Structure:

Interacts with TYROBP/DAP12. Interacts with KMT2E isoform NKp44L.

Family&Domains:

Belongs to the natural cytotoxicity receptor (NCR) family.

Research Fields

· Organismal Systems > Immune system > Natural killer cell mediated cytotoxicity.   (View pathway)

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.