NDUFS4 Antibody - #DF9670
| Product: | NDUFS4 Antibody |
| Catalog: | DF9670 |
| Description: | Rabbit polyclonal antibody to NDUFS4 |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 20 kDa; 20kD(Calculated). |
| Uniprot: | O43181 |
| RRID: | AB_2842866 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9670, RRID:AB_2842866.
Fold/Unfold
AQDQ; CI 18; CI 18 kDa; CI AQDQ; CI-18 kDa; CI-AQDQ; Complex I 18 kDa; Complex I AQDQ; Complex I-18 kDa; Complex I-AQDQ; mitochondrial; mitochondrial respiratory chain complex I (18 KD subunit); NADH coenzyme Q reductase; NADH dehydrogenase (ubiquinone) Fe S protein 4 18kDa; NADH dehydrogenase [ubiquinone] iron-sulfur protein 4; NADH dehydrogenase; NADH ubiquinone oxidoreductase 18 kDa subunit; NADH-ubiquinone oxidoreductase 18 kDa subunit; NDUFS4; NDUS4_HUMAN;
Immunogens
- O43181 NDUS4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAVSMSVVLRQTLWRRRAVAVAALSVSRVPTRSLRTSTWRLAQDQTQDTQLITVDEKLDITTLTGVPEEHIKTRKVRIFVPARNNMQSGVNNTKKWKMEFDTRERWENPLMGWASTADPLSNMVLTFSTKEDAVSFAEKNGWSYDIEERKVPKPKSKSYGANFSWNKRTRVSTK
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O43181 As Substrate
Research Backgrounds
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Mitochondrion inner membrane>Peripheral membrane protein>Matrix side.
Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
Belongs to the complex I NDUFS4 subunit family.
Research Fields
· Human Diseases > Endocrine and metabolic diseases > Non-alcoholic fatty liver disease (NAFLD).
· Human Diseases > Neurodegenerative diseases > Alzheimer's disease.
· Human Diseases > Neurodegenerative diseases > Parkinson's disease.
· Human Diseases > Neurodegenerative diseases > Huntington's disease.
· Metabolism > Energy metabolism > Oxidative phosphorylation.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Nervous system > Retrograde endocannabinoid signaling. (View pathway)
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