NNT Antibody - #DF9658
| Product: | NNT Antibody |
| Catalog: | DF9658 |
| Description: | Rabbit polyclonal antibody to NNT |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 114kDa; 114kD(Calculated). |
| Uniprot: | Q13423 |
| RRID: | AB_2842854 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9658, RRID:AB_2842854.
Fold/Unfold
GCCD4; mitochondrial; NAD(P) transhydrogenase; NAD(P) transhydrogenase mitochondrial; Nicotinamide nucleotide transhydrogenase; NNT; NNTM; NNTM_HUMAN; Pyridine nucleotide transhydrogenase;
Immunogens
Widely expressed with expression most readily detectable in adrenal, heart, kidney, thyroid and adipose tissues.
- Q13423 NNTM_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MANLLKTVVTGCSCPLLSNLGSCKGLRVKKDFLRTFYTHQELWCKAPVKPGIPYKQLTVGVPKEIFQNEKRVALSPAGVQNLVKQGFNVVVESGAGEASKFSDDHYRVAGAQIQGAKEVLASDLVVKVRAPMVNPTLGVHEADLLKTSGTLISFIYPAQNPELLNKLSQRKTTVLAMDQVPRVTIAQGYDALSSMANIAGYKAVVLAANHFGRFFTGQITAAGKVPPAKILIVGGGVAGLASAGAAKSMGAIVRGFDTRAAALEQFKSLGAEPLEVDLKESGEGQGGYAKEMSKEFIEAEMKLFAQQCKEVDILISTALIPGKKAPVLFNKEMIESMKEGSVVVDLAAEAGGNFETTKPGELYIHKGITHIGYTDLPSRMATQASTLYSNNITKLLKAISPDKDNFYFDVKDDFDFGTMGHVIRGTVVMKDGKVIFPAPTPKNIPQGAPVKQKTVAELEAEKAATITPFRKTMSTASAYTAGLTGILGLGIAAPNLAFSQMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGLTAVGGLALMGGHLYPSTTSQGLAALAAFISSVNIAGGFLVTQRMLDMFKRPTDPPEYNYLYLLPAGTFVGGYLAALYSGYNIEQIMYLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLAATLGVLKPGPELLAQMSGAMALGGTIGLTIAKRIQISDLPQLVAAFHSLVGLAAVLTCIAEYIIEYPHFATDAAANLTKIVAYLGTYIGGVTFSGSLIAYGKLQGLLKSAPLLLPGRHLLNAGLLAASVGGIIPFMVDPSFTTGITCLGSVSALSAVMGVTLTAAIGGADMPVVITVLNSYSGWALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGGKPMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKMLTEQGKKVRFGIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTDLVLVIGANDTVNSAAQEDPNSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKVRESYQK
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q13423 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K49 | Ubiquitination | Uniprot | |
| K55 | Ubiquitination | Uniprot | |
| K63 | Acetylation | Uniprot | |
| K70 | Acetylation | Uniprot | |
| S75 | Phosphorylation | Uniprot | |
| K100 | Acetylation | Uniprot | |
| K117 | Acetylation | Uniprot | |
| S122 | Phosphorylation | Uniprot | |
| T150 | Phosphorylation | Uniprot | |
| K202 | Acetylation | Uniprot | |
| K267 | Ubiquitination | Uniprot | |
| K279 | Ubiquitination | Uniprot | |
| K323 | Acetylation | Uniprot | |
| K331 | Acetylation | Uniprot | |
| T369 | Phosphorylation | Uniprot | |
| Y373 | Phosphorylation | Uniprot | |
| T374 | Phosphorylation | Uniprot | |
| T382 | Phosphorylation | Uniprot | |
| T393 | Phosphorylation | Uniprot | |
| K394 | Acetylation | Uniprot | |
| K397 | Acetylation | Uniprot | |
| K403 | Ubiquitination | Uniprot | |
| Y407 | Phosphorylation | Uniprot | |
| T440 | Phosphorylation | Uniprot | |
| K442 | Ubiquitination | Uniprot | |
| K451 | Ubiquitination | Uniprot | |
| K462 | Ubiquitination | Uniprot | |
| S677 | Phosphorylation | Uniprot | |
| S769 | Phosphorylation | Uniprot | |
| Y942 | Phosphorylation | Uniprot | |
| K1059 | Acetylation | Uniprot | |
| K1070 | Acetylation | Uniprot | |
| K1071 | Acetylation | Uniprot | |
| K1079 | Ubiquitination | Uniprot |
Research Backgrounds
The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity). May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland.
Mitochondrion inner membrane>Multi-pass membrane protein>Matrix side.
Widely expressed with expression most readily detectable in adrenal, heart, kidney, thyroid and adipose tissues.
Homodimer.
In the N-terminal section; belongs to the AlaDH/PNT family.
In the C-terminal section; belongs to the PNT beta subunit family.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.