IMMP2L Antibody - #DF9630
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9630, RRID:AB_2842826.
Fold/Unfold
EC 3.4.21; IMP2; IMP2 inner mitochondrial membrane peptidase like (S. cerevisiae); IMP2 inner mitochondrial membrane protease like (S. cerevisiae); IMP2 inner mitochondrial membrane protease like; IMP2 like; IMP2 like protein; IMP2-LIKE; Inner mitochondrial membrane peptidase 2 like; Mitochondrial inner membrane protease subunit 2; OTTHUMP00000207168; OTTHUMP00000207189;
Immunogens
- Q96T52 IMP2L_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAQSQGWVKRYIKAFCKGFFVAVPVAVTFLDRVACVARVEGASMQPSLNPGGSQSSDVVLLNHWKVRNFEVHRGDIVSLVSPKNPEQKIIKRVIALEGDIVRTIGHKNRYVKVPRGHIWVEGDHHGHSFDSNSFGPVSLGLLHAHATHILWPPERWQKLESVLPPERLPVQREEE
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q96T52 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S43 | Phosphorylation | Uniprot | |
| S47 | Phosphorylation | Uniprot | |
| K83 | Ubiquitination | Uniprot | |
| K88 | Ubiquitination | Uniprot | |
| K112 | Methylation | Uniprot |
Research Backgrounds
Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
Mitochondrion inner membrane>Single-pass membrane protein.
Expressed in all tissues tested except adult liver and lung.
Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
Belongs to the peptidase S26 family. IMP2 subfamily.
Research Fields
· Genetic Information Processing > Folding, sorting and degradation > Protein export.
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