Product: IMMP1L Antibody
Catalog: DF9629
Description: Rabbit polyclonal antibody to IMMP1L
Application: WB IF/ICC
Reactivity: Human, Mouse
Prediction: Pig, Zebrafish, Horse, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 19 kDa; 19kD(Calculated).
Uniprot: Q96LU5
RRID: AB_2842825

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Product Info

Source:
Rabbit
Application:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(82%), Zebrafish(91%), Horse(82%), Rabbit(91%), Dog(91%), Chicken(91%), Xenopus(82%)
Clonality:
Polyclonal
Specificity:
IMMP1L Antibody detects endogenous levels of total IMMP1L.
RRID:
AB_2842825
Cite Format: Affinity Biosciences Cat# DF9629, RRID:AB_2842825.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Immp1l; IMP 1; IMP 1 like; IMP1; IMP1 inner mitochondrial membrane peptidase like; IMP1 like; IMP1-like protein; IMP1L_HUMAN; Mitochondrial inner membrane protease subunit 1;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MLRGVLGKTFRLVGYTIQYGCIAHCAFEYVGGVVMCSGPSMEPTIQNSDIVFAENLSRHFYGIQRGDIVIAKSPSDPKSNICKRVIGLEGDKILTTSPSDFFKSHSYVPMGHVWLEGDNLQNSTDSRCYGPIPYGLIRGRIFFKIWPLSDFGFLRASPNGHRFSDD

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Zebrafish
91
Dog
91
Chicken
91
Rabbit
91
Pig
82
Horse
82
Xenopus
82
Sheep
73
Bovine
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q96LU5 As Substrate

Site PTM Type Enzyme
S104 Phosphorylation
S106 Phosphorylation
Y107 Phosphorylation

Research Backgrounds

Function:

Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.

Subcellular Location:

Mitochondrion inner membrane.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Heterodimer of 2 subunits, IMMPL1 and IMMPL2.

Family&Domains:

Belongs to the peptidase S26 family. IMP1 subfamily.

Research Fields

· Genetic Information Processing > Folding, sorting and degradation > Protein export.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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