ACSL5 Antibody - #DF9607
|Reactivity:||Human, Mouse, Rat|
|Prediction:||Pig, Horse, Rabbit|
*The optimal dilutions should be determined by the end user.
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9607, RRID:AB_2842803.
ACS2; ACS5; Acyl CoA synthetase 5; Acyl CoA synthetase long chain family member 5; EC 220.127.116.11; FACL5; FACL5 for fatty acid coenzyme A ligase 5; Fatty acid CoA ligase, long chain 5; Fatty acid coenzyme A ligase 5; Fatty acid Coenzyme A ligase long chain 5; LACS 5; Long chain acyl CoA synthetase 5; Long chain fatty acid CoA ligase 5; Long chain fatty acid coenzyme A ligase 5;
- Q9ULC5 ACSL5_HUMAN:
- Protein BLAST With
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9ULC5 As Substrate
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage (By similarity). Utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids (By similarity). It was suggested that it may also stimulate fatty acid oxidation (By similarity). At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL. May have a role in the survival of glioma cells.
Mitochondrion. Endoplasmic reticulum. Mitochondrion outer membrane>Single-pass type III membrane protein. Endoplasmic reticulum membrane>Single-pass type III membrane protein. Cell membrane.
Belongs to the ATP-dependent AMP-binding enzyme family.
· Cellular Processes > Transport and catabolism > Peroxisome. (View pathway)
· Cellular Processes > Cell growth and death > Ferroptosis. (View pathway)
· Metabolism > Lipid metabolism > Fatty acid biosynthesis.
· Metabolism > Lipid metabolism > Fatty acid degradation.
· Metabolism > Global and overview maps > Metabolic pathways.
· Metabolism > Global and overview maps > Fatty acid metabolism.
· Organismal Systems > Endocrine system > PPAR signaling pathway.
· Organismal Systems > Endocrine system > Adipocytokine signaling pathway.
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