A4GALT Antibody - #DF9602
| Product: | A4GALT Antibody |
| Catalog: | DF9602 |
| Description: | Rabbit polyclonal antibody to A4GALT |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Sheep, Rabbit, Dog |
| Mol.Wt.: | 40 kDa; 40kD(Calculated). |
| Uniprot: | Q9NPC4 |
| RRID: | AB_2842798 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9602, RRID:AB_2842798.
Fold/Unfold
4 N acetylglucosaminyltransferase; 4-galactosyltransferase; 4-N-acetylglucosaminyltransferase; A14GALT; A4GALT; A4GALT1; A4GAT_HUMAN; Alpha 1 4 galactosyltransferase; Alpha 1 4 N acetylglucosaminyltransferase; Alpha-1; Alpha4Gal T1; Alpha4Gal-T1; CD77 synthase; Gb3 synthase; Gb3S; Globotriaosylceramide synthase; Lactosylceramide 4 alpha galactosyltransferase; Lactosylceramide 4-alpha-galactosyltransferase; P blood group (P one antigen); P(k) antigen synthase; P1; P1/Pk synthase; PK; UDP galactose beta D galactosyl beta1 R 4 alpha D galactosyltransferase; UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase;
Immunogens
Ubiquitous. Highly expressed in kidney, heart, spleen, liver, testis and placenta.
- Q9NPC4 A4GAT_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSKPPDLLLRLLRGAPRQRVCTLFIIGFKFTFFVSIMIYWHVVGEPKEKGQLYNLPAEIPCPTLTPPTPPSHGPTPGNIFFLETSDRTNPNFLFMCSVESAARTHPESHVLVLMKGLPGGNASLPRHLGISLLSCFPNVQMLPLDLRELFRDTPLADWYAAVQGRWEPYLLPVLSDASRIALMWKFGGIYLDTDFIVLKNLRNLTNVLGTQSRYVLNGAFLAFERRHEFMALCMRDFVDHYNGWIWGHQGPQLLTRVFKKWCSIRSLAESRACRGVTTLPPEAFYPIPWQDWKKYFEDINPEELPRLLSATYAVHVWNKKSQGTRFEATSRALLAQLHARYCPTTHEAMKMYL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NPC4 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Phosphorylation | Uniprot | |
| T63 | Phosphorylation | Uniprot | |
| T84 | Phosphorylation | Uniprot | |
| S85 | Phosphorylation | Uniprot | |
| T104 | Phosphorylation | Uniprot | |
| R179 | Methylation | Uniprot | |
| S321 | Phosphorylation | Uniprot | |
| Y341 | Phosphorylation | Uniprot |
Research Backgrounds
Catalyzes the transfer of galactose from UDP-alpha-D-galactose to lactosylceramide/beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide(d18:1(4E)) to produce globotriaosylceramide/globoside Gb3Cer (d18:1(4E)). Also able to transfer galactose to galactosylceramide/beta-D-Gal-(1<->1')-Cer. Globoside Gb3Cer is a glycosphingolipid of the globo serie, one of the major types of neutral root structures of glycosphingolipids, that constitute a significant portion of mammalian cell membranes (Probable). Globotriaosylceramide/globoside Gb3Cer in blood and tissue cell membranes is the antigen Pk of blood histogroup P.
(Microbial infection) Globotriaosylceramide is one of the cellular ligands for bacterial verotoxins.
Golgi apparatus membrane>Single-pass type II membrane protein.
Ubiquitous. Highly expressed in kidney, heart, spleen, liver, testis and placenta.
The conserved DXD motif is involved in enzyme activity.
Belongs to the glycosyltransferase 32 family.
Research Fields
· Metabolism > Glycan biosynthesis and metabolism > Glycosphingolipid biosynthesis - lacto and neolacto series.
· Metabolism > Glycan biosynthesis and metabolism > Glycosphingolipid biosynthesis - globo and isoglobo series.
· Metabolism > Global and overview maps > Metabolic pathways.
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