KIR2DL2 Antibody | Affinity Biosciences

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Western blot analysis of KIR2DL2 using NIH-3T3 whole cell lysates.

Product:	KIR2DL2 Antibody
Catalog:	DF9599
Description:	Rabbit polyclonal antibody to KIR2DL2
Application:	WB
Reactivity:	Human, Mouse
Mol.Wt.:	38 kDa; 38kD(Calculated).
Uniprot:	P43627
RRID:	AB_2842795

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

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Related Downloads

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human,Mouse

Clonality:

Polyclonal

Specificity:

KIR2DL2 Antibody detects endogenous levels of total KIR2DL2.

RRID:

AB_2842795
Cite Format: Affinity Biosciences Cat# DF9599, RRID:AB_2842795.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

CD158 antigen-like family member B1; CD158b; CD158b1; KI2L2_HUMAN; Killer cell immunoglobulin like receptor two domains long cytoplasmic tail 2; Killer cell immunoglobulin-like receptor 2DL2; KIR2DL2; MHC class I NK cell receptor; Natural killer-associated transcript 6; NKAT 6; NKAT-6; NKAT6; p58 natural killer cell receptor clone CL-43; p58 NK receptor CL-43; p58.2;

Immunogens

Immunogen:

Uniprot:

P43627(KI2L2_HUMAN) >>Visit HPA database.

Gene(ID):

KIR2DL2(3803)

Sequence:

P43627 KI2L2_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVIGNPSNSWPSPTEPSSKTGNPRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYAELPNAESRSKVVSCP

PTMs - P43627 As Substrate

P43627

Site	PTM Type	Source
S30	Phosphorylation	Uniprot
S86	Phosphorylation	Uniprot
Y98	Phosphorylation	Uniprot
T138	Phosphorylation	Uniprot
S150	Phosphorylation	Uniprot
S151	Phosphorylation	Uniprot
T180	Phosphorylation	Uniprot
S281	Phosphorylation	Uniprot
Y302	Phosphorylation	Uniprot
T311	Phosphorylation	Uniprot

Research Backgrounds

P43627_KI2L2_HUMAN

Function:

Receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis.

Subcellular Location:

Cell membrane>Single-pass type I membrane protein.

Family&Domains:

Belongs to the immunoglobulin superfamily.

Research Fields

· Cellular Processes > Cell growth and death > Cellular senescence. (View pathway)

· Human Diseases > Immune diseases > Graft-versus-host disease.

· Organismal Systems > Immune system > Antigen processing and presentation. (View pathway)

· Organismal Systems > Immune system > Natural killer cell mediated cytotoxicity. (View pathway)

Restrictive clause

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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KIR2DL2 Antibody - #DF9599