ELOVL2 Antibody - #DF9495
| Product: | ELOVL2 Antibody |
| Catalog: | DF9495 |
| Description: | Rabbit polyclonal antibody to ELOVL2 |
| Application: | WB |
| Reactivity: | Human |
| Prediction: | Zebrafish, Horse, Rabbit, Dog, Xenopus |
| Mol.Wt.: | 35 kDa; 35kD(Calculated). |
| Uniprot: | Q9NXB9 |
| RRID: | AB_2842691 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9495, RRID:AB_2842691.
Fold/Unfold
3 keto acyl CoA synthase ELOVL2; 3-keto acyl-CoA synthase Elovl2; Elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast) like 2; Elongation of very long chain fatty acids protein 2; ELOV2_HUMAN; ELOVL fatty acid elongase 2; Elovl2; FLJ20334; OTTHUMP00000016029; SSC2;
Immunogens
- Q9NXB9 ELOV2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEHLKAFDDEINAFLDNMFGPRDSRVRGWFMLDSYLPTFFLTVMYLLSIWLGNKYMKNRPALSLRGILTLYNLGITLLSAYMLAELILSTWEGGYNLQCQDLTSAGEADIRVAKVLWWYYFSKSVEFLDTIFFVLRKKTSQITFLHVYHHASMFNIWWCVLNWIPCGQSFFGPTLNSFIHILMYSYYGLSVFPSMHKYLWWKKYLTQAQLVQFVLTITHTMSAVVKPCGFPFGCLIFQSSYMLTLVILFLNFYVQTYRKKPMKKDMQEPPAGKEVKNGFSKAYFTAANGVMNKKAQ
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NXB9 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K293 | Acetylation | Uniprot |
Research Backgrounds
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA), acting specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. May participate in the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
Endoplasmic reticulum membrane>Multi-pass membrane protein.
Liver and testis.
The C-terminal di-lysine motif may confer endoplasmic reticulum localization.
Belongs to the ELO family. ELOVL2 subfamily.
Research Fields
· Metabolism > Lipid metabolism > Fatty acid elongation.
· Metabolism > Lipid metabolism > Biosynthesis of unsaturated fatty acids.
· Metabolism > Global and overview maps > Fatty acid metabolism.
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