Product: DNAL4 Antibody
Catalog: DF9470
Description: Rabbit polyclonal antibody to DNAL4
Application: WB IHC IF/ICC
Reactivity: Human, Mouse
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 12 kDa; 12kD(Calculated).
Uniprot: O96015
RRID: AB_2842666

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Product Info

Source:
Rabbit
Application:
IF/ICC 1:100-1:500, WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Bovine(100%), Horse(88%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
DNAL4 Antibody detects endogenous levels of total DNAL4.
RRID:
AB_2842666
Cite Format: Affinity Biosciences Cat# DF9470, RRID:AB_2842666.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

D15Ertd424e; Dnal4; DNAL4_HUMAN; Dnalc4; Dynein axonemal light chain 4; Dynein light chain 4, axonemal; Dynein light chain, outer arm 4; Dynein, axonemal, light 4; Dynein, axonemal, light polypeptide 4; MGC105573; PIG27; Proliferation inducing gene 27; Proliferation inducing protein 27;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MGETEGKKDEADYKRLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWKCS

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Chicken
100
Rabbit
100
Horse
88
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O96015 As Substrate

Site PTM Type Enzyme
K55 Ubiquitination

Research Backgrounds

Function:

Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity (By similarity).

Subcellular Location:

Cytoplasm>Cytoskeleton>Cilium axoneme.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Consists of at least two heavy chains and a number of intermediate and light chains.

Family&Domains:

Belongs to the dynein light chain family.

Research Fields

· Human Diseases > Neurodegenerative diseases > Huntington's disease.

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