DLG3 Antibody - #DF9443

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Product: DLG3 Antibody
Catalog: DF9443
Description: Rabbit polyclonal antibody to DLG3
Application: WB
Reactivity: Human, Mouse, Rat
Prediction: Pig, Zebrafish, Bovine, Sheep, Rabbit, Dog, Chicken
Mol.Wt.: 90 kDa; 90kD(Calculated).
Uniprot: Q92796
RRID: AB_2842639

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 100ul $280 In stock
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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Zebrafish(82%), Bovine(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%)
Clonality:
Polyclonal
Specificity:
DLG3 Antibody detects endogenous levels of total DLG3.
RRID:
AB_2842639
Cite Format: Affinity Biosciences Cat# DF9443, RRID:AB_2842639.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

bA291O7.3; bA291O7.3 discs large Drosophila homolog 3 neuroendocrine dlg; Discs large Drosophila homolog 3; Discs large homolog 3 neuroendocrine dlg Drosophila; Discs large homolog 3; Discs large homolog 3 Drosophila; Discs, large homolog 3 (Drosophila); Disks large homolog 3; DLG 3; Dlg3; DLG3_HUMAN; KIAA1232; mKIAA1232; MRX 90; MRX; MRX90; NE Dlg; NEDLG; Neuroendocrine dlg; Neuroendocrine-DLG; OTTHUMP00000023475; OTTHUMP00000023476; OTTHUMP00000023477; SAP 102; SAP-102; SAP102; Synapse associated protein 102; Synapse-associated protein 102; XLMR;

Immunogens

Immunogen:
Uniprot:

Q92796(DLG3_HUMAN) >>Visit HPA database.

Gene(ID):
DLG3(1741)
Sequence:
MHKHQHCCKCPECYEVTRLAALRRLEPPGYGDWQVPDPYGPGGGNGASAGYGGYSSQTLPSQAGATPTPRTKAKLIPTGRDVGPVPPKPVPGKSTPKLNGSGPSWWPECTCTNRDWYEQVNGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLVVRRRQPPPETIMEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKVAKPGSLHLNDMYAPPDYASTFTALADNHISHNSSLGYLGAVESKVSYPAPPQVPPTRYSPIPRHMLAEEDFTREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLSDDYYGAKNLKGQEDAILSYEPVTRQEIHYARPVIILGPMKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPSPEKL

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
100
Zebrafish
82
Horse
0
Xenopus
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q92796 As Substrate

Site PTM Type Enzyme
T78 Phosphorylation
T112 Phosphorylation
Y117 Phosphorylation
S123 Phosphorylation
T163 Phosphorylation
K268 Ubiquitination
Y306 Phosphorylation
S458 Phosphorylation
S487 Phosphorylation
S488 Phosphorylation
S490 Phosphorylation
S491 Phosphorylation
S495 Phosphorylation
S503 Phosphorylation
Y505 Phosphorylation
T515 Phosphorylation
T550 Phosphorylation
S589 Phosphorylation
Y626 Phosphorylation
K637 Ubiquitination
T660 Phosphorylation
Y673 Phosphorylation
S678 Phosphorylation
T759 Phosphorylation
Y760 Phosphorylation
K765 Acetylation
Y808 Phosphorylation
S813 Phosphorylation

Research Backgrounds

Function:

Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling.

Subunit Structure:

Interacts through its PDZ domains with NETO1, GRIN2B and SYNGAP1. Interacts through its guanylate kinase-like domain with DLGAP1, DLGAP2, DLGAP3 and DLGAP4. Interacts with FLTP/C1orf192 (By similarity). Interacts through its PDZ domains with APC. Interacts through its first two PDZ domains with ERBB4. Interacts through its third PDZ domain with NLGN1, and probably with NLGN2 and NLGN3. Interacts with FRMPD4 (via C-terminus). Interacts with LRFN1, LRFN2 and LRFN4.

Family&Domains:

Belongs to the MAGUK family.

Research Fields

· Cellular Processes > Cellular community - eukaryotes > Tight junction.   (View pathway)

· Environmental Information Processing > Signal transduction > Hippo signaling pathway.   (View pathway)

· Human Diseases > Infectious diseases: Viral > Human papillomavirus infection.

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