BAAT Antibody - #DF9277
| Product: | BAAT Antibody |
| Catalog: | DF9277 |
| Description: | Rabbit polyclonal antibody to BAAT |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Prediction: | Horse, Dog |
| Mol.Wt.: | 46 kDa; 46kD(Calculated). |
| Uniprot: | Q14032 |
| RRID: | AB_2842473 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9277, RRID:AB_2842473.
Fold/Unfold
FLJ20300; BAAT; BAAT_HUMAN; BACAT; BAT; Bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase); Bile acid CoA:amino acid N acyltransferase; Bile acid Coenzyme A amino acid N acyltransferase glycine N choloyltransferase; Bile acid Coenzyme A: amino acid N acyltransferase; Bile acid-CoA:amino acid N-acyltransferase; Glycine N choloyltransferase; Glycine N-choloyltransferase; Long chain fatty acyl CoA hydrolase; Long-chain fatty-acyl-CoA hydrolase; MGC104432;
Immunogens
- Q14032 BAAT_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MIQLTATPVSALVDEPVHIRATGLIPFQMVSFQASLEDENGDMFYSQAHYRANEFGEVDLNHASSLGGDYMGVHPMGLFWSLKPEKLLTRLLKRDVMNRPFQVQVKLYDLELIVNNKVASAPKASLTLERWYVAPGVTRIKVREGRLRGALFLPPGEGLFPGVIDLFGGLGGLLEFRASLLASRGFASLALAYHNYEDLPRKPEVTDLEYFEEAANFLLRHPKVFGSGVGVVSVCQGVQIGLSMAIYLKQVTATVLINGTNFPFGIPQVYHGQIHQPLPHSAQLISTNALGLLELYRTFETTQVGASQYLFPIEEAQGQFLFIVGEGDKTINSKAHAEQAIGQLKRHGKNNWTLLSYPGAGHLIEPPYSPLCCASTTHDLRLHWGGEVIPHAAAQEHAWKEIQRFLRKHLIPDVTSQL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q14032 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y132 | Phosphorylation | Uniprot | |
| T138 | Phosphorylation | Uniprot | |
| Y196 | Phosphorylation | Uniprot | |
| Y210 | Phosphorylation | Uniprot | |
| S307 | Phosphorylation | Uniprot | |
| Y309 | Phosphorylation | Uniprot | |
| K334 | Acetylation | Uniprot | |
| K345 | Acetylation | Uniprot |
Research Backgrounds
Catalyzes the amidation of bile acids (BAs) with the amino acids taurine and glycine. More than 95% of the BAs are N-acyl amidates with glycine and taurine. Amidation of BAs in the liver with glycine or taurine prior to their excretion into bile is an important biochemical event in bile acid metabolism. This conjugation (or amidation) plays several important biological roles in that it promotes the secretion of BAs and cholesterol into bile and increases the detergent properties of BAs in the intestine, which facilitates lipid and vitamin absorption. May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.
Cytoplasm>Cytosol. Peroxisome.
Expressed in liver, gallbladder mucosa and pancreas.
Monomer.
Belongs to the C/M/P thioester hydrolase family.
Research Fields
· Cellular Processes > Transport and catabolism > Peroxisome. (View pathway)
· Metabolism > Lipid metabolism > Primary bile acid biosynthesis.
· Metabolism > Metabolism of other amino acids > Taurine and hypotaurine metabolism.
· Metabolism > Lipid metabolism > Biosynthesis of unsaturated fatty acids.
· Metabolism > Global and overview maps > Metabolic pathways.
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