GCNT4 Antibody - #DF9268
| Product: | GCNT4 Antibody |
| Catalog: | DF9268 |
| Description: | Rabbit polyclonal antibody to GCNT4 |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Bovine, Horse, Sheep, Dog |
| Mol.Wt.: | 53kDa; 53kD(Calculated). |
| Uniprot: | Q9P109 |
| RRID: | AB_2842464 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9268, RRID:AB_2842464.
Fold/Unfold
Core 2 (beta-1,6-N-acetylglucosaminyltransferase); Core 2 branching enzyme 3; Core2 GlcNAc transferase 3; GCNT4; Glucosaminyl (N-acetyl) transferase 4;
Immunogens
Predominantly expressed in thymus. Weakly expressed in pancreas, peripheral blood leukocytes, placenta, small intestine and stomach. Barely detectable in liver, spleen, lung and lymph node.
- Q9P109 GCNT4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKIFKCYFKHTLQQKVFILFLTLWLLSLLKLLNVRRLFPQKDIYLVEYSLSTSPFVRNRYTHVKDEVRYEVNCSGIYEQEPLEIGKSLEIRRRDIIDLEDDDVVAMTSDCDIYQTLRGYAQKLVSKEEKSFPIAYSLVVHKDAIMVERLIHAIYNQHNIYCIHYDRKAPDTFKVAMNNLAKCFSNIFIASKLEAVEYAHISRLQADLNCLSDLLKSSIQWKYVINLCGQDFPLKSNFELVSELKKLNGANMLETVKPPNSKLERFTYHHELRRVPYEYVKLPIRTNISKEAPPHNIQIFVGSAYFVLSQAFVKYIFNNSIVQDFFAWSKDTYSPDEHFWATLIRVPGIPGEISRSAQDVSDLQSKTRLVKWNYYEGFFYPSCTGSHLRSVCIYGAAELRWLIKDGHWFANKFDSKVDPILIKCLAEKLEEQQRDWITLPSEKLFMDRNLTTTS
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9P109 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K41 | Acetylation | Uniprot | |
| Y48 | Phosphorylation | Uniprot | |
| Y60 | Phosphorylation | Uniprot | |
| Y135 | Phosphorylation | Uniprot | |
| Y379 | Phosphorylation | Uniprot | |
| S381 | Phosphorylation | Uniprot | |
| T383 | Phosphorylation | Uniprot | |
| S385 | Phosphorylation | Uniprot |
Research Backgrounds
Glycosyltransferase that mediates core 2 O-glycan branching, an important step in mucin-type biosynthesis. Does not have core 4 O-glycan or I-branching enzyme activity.
Golgi apparatus membrane>Single-pass type II membrane protein.
Predominantly expressed in thymus. Weakly expressed in pancreas, peripheral blood leukocytes, placenta, small intestine and stomach. Barely detectable in liver, spleen, lung and lymph node.
Belongs to the glycosyltransferase 14 family.
Research Fields
· Metabolism > Glycan biosynthesis and metabolism > Mucin type O-glycan biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
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