AQP6 Antibody - #DF9223
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9223, RRID:AB_2842419.
Fold/Unfold
AQP-6; AQP2L; Aqp6; AQP6_HUMAN; Aquaporin 2 like; aquaporin 2 like kidney specific; Aquaporin 6; Aquaporin 6 kidney specific; Aquaporin-2-like; Aquaporin-6; hKID; Human kidney water channel (hKID) mRNA, complete cds; KID; Kidney-specific aquaporin;
Immunogens
- Q13520 AQP6_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDAVEPGGRGWASMLACRLWKAISRALFAEFLATGLYVFFGVGSVMRWPTALPSVLQIAITFNLVTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPGDIRETLGINVVRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQTSGSPATMIGISVALGHLIGIHFTGCSMNPARSFGPAIIIGKFTVHWVFWVGPLMGALLASLIYNFVLFPDTKTLAQRLAILTGTVEVGTGAGAGAEPLKKESQPGSGAVEMESV
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q13520 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S228 | Phosphorylation | Uniprot | |
| Y231 | Phosphorylation | Uniprot |
Research Backgrounds
Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism.
Cytoplasmic vesicle membrane>Multi-pass membrane protein.
Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
Belongs to the MIP/aquaporin (TC 1.A.8) family.
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