Product: ALDH3B2 Antibody
Catalog: DF9188
Description: Rabbit polyclonal antibody to ALDH3B2
Application: WB IHC IF/ICC
Reactivity: Human
Prediction: Zebrafish, Horse, Dog
Mol.Wt.: 43 kDa; 43kD(Calculated).
Uniprot: P48448
RRID: AB_2842384

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, IF/ICC 1:100-1:500, WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Zebrafish(83%), Horse(88%), Dog(100%)
Clonality:
Polyclonal
Specificity:
ALDH3B2 Antibody detects endogenous levels of total ALDH3B2.
RRID:
AB_2842384
Cite Format: Affinity Biosciences Cat# DF9188, RRID:AB_2842384.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Acetaldehyde dehydrogenase 8; AL3B2_HUMAN; Aldehyde dehydrogenase 3 family, member B2; Aldehyde dehydrogenase 8; Aldehyde dehydrogenase family 3 member B2; ALDH3B2; ALDH8; OTTHUMP00000235616;

Immunogens

Immunogen:
Uniprot:
Expression:
P48448 AL3B2_HUMAN:

Salivary gland.

Sequence:
MKDEPRSTNLFMKLDSVFIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQYLDQSCFAVVLGGPQETGQLLEHKLDYIFFTGSPRVGKIVMTAATKHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLPALQSTITRFYGDDPQSSPNLGHIINQKQFQRLRALLGCSRVAIGGQSNESDRYIAPTVLVDVQETEPVMQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFGGNEGFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLAPSGLEKLKEIHYPPYTDWNQQLLRWGMGSQSCTLL

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
100
Horse
88
Zebrafish
83
Pig
71
Bovine
71
Sheep
71
Xenopus
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P48448 As Substrate

Site PTM Type Enzyme
T117 Phosphorylation
T124 Phosphorylation
T127 Phosphorylation
K133 Ubiquitination
K208 Ubiquitination
Y362 Phosphorylation
Y365 Phosphorylation

Research Backgrounds

Function:

Oxidizes medium and long chain aldehydes into non-toxic fatty acids.

PTMs:

Geranylgeranylation is important for localization to lipid droplets and enzyme activity.

Subcellular Location:

Lipid droplet.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Salivary gland.

Family&Domains:

Belongs to the aldehyde dehydrogenase family.

Restrictive clause

 

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For Research Use Only.
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