AGXT2 Antibody - #DF9184
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Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF9184, RRID:AB_2842380.
Fold/Unfold
(R)-3-amino-2-methylpropionate--pyruvate transaminase; AGT2; AI303810; AI663818; Alanine glyoxylate aminotransferase 2; Alanine glyoxylate aminotransferase 2 mitochondrial; Beta-ALAAT II; Beta-alanine-pyruvate aminotransferase; DAIBAT;
Immunogens
- Q9BYV1 AGT2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTLIWRHLLRPLCLVTSAPRILEMHPFLSLGTSRTSVTKLSLHTKPRMPPCDFMPERYQSLGYNRVLEIHKEHLSPVVTAYFQKPLLLHQGHMEWLFDAEGSRYLDFFSGIVTVSVGHCHPKVNAVAQKQLGRLWHTSTVFFHPPMHEYAEKLAALLPEPLKVIFLVNSGSEANELAMLMARAHSNNIDIISFRGAYHGCSPYTLGLTNVGTYKMELPGGTGCQPTMCPDVFRGPWGGSHCRDSPVQTIRKCSCAPDCCQAKDQYIEQFKDTLSTSVAKSIAGFFAEPIQGVNGVVQYPKGFLKEAFELVRARGGVCIADEVQTGFGRLGSHFWGFQTHDVLPDIVTMAKGIGNGFPMAAVITTPEIAKSLAKCLQHFNTFGGNPMACAIGSAVLEVIKEENLQENSQEVGTYMLLKFAKLRDEFEIVGDVRGKGLMIGIEMVQDKISCRPLPREEVNQIHEDCKHMGLLVGRGSIFSQTFRIAPSMCITKPEVDFAVEVFRSALTQHMERRAK
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9BYV1 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y58 | Phosphorylation | Uniprot | |
| Y63 | Phosphorylation | Uniprot | |
| K129 | Acetylation | Uniprot | |
| T212 | Phosphorylation | Uniprot | |
| K270 | Acetylation | Uniprot | |
| Y298 | Phosphorylation | Uniprot | |
| S448 | Phosphorylation | Uniprot |
Research Backgrounds
Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure.
Mitochondrion.
Homotetramer.
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Research Fields
· Metabolism > Amino acid metabolism > Alanine, aspartate and glutamate metabolism.
· Metabolism > Amino acid metabolism > Glycine, serine and threonine metabolism.
· Metabolism > Amino acid metabolism > Cysteine and methionine metabolism.
· Metabolism > Amino acid metabolism > Valine, leucine and isoleucine degradation.
· Metabolism > Global and overview maps > Metabolic pathways.
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